Dietary Pyridoxine Controls Efficacy of Vitamin B<sub>6</sub>-Auxotrophic Tuberculosis Vaccine Bacillus Calmette-Guérin Δ<italic toggle="yes">ureC</italic>::<italic toggle="yes">hly</italic> Δ<italic toggle="yes">pdx1</italic> in Mice

Dietary Pyridoxine Controls Efficacy of Vitamin B<sub>6</sub>-Auxotrophic Tuberculosis Vaccine Bacillus Calmette-Guérin Δ<italic toggle="yes">ureC</italic>::<italic toggle="yes">hly</italic> Δ<italic toggle="yes">pdx1</italic> in Mice

ABSTRACT The only tuberculosis (TB) vaccine in use today, bacillus Calmette-Guérin (BCG), provides insufficient protection and can cause adverse events in immunocompromised individuals, such as BCGosis in HIV+ newborns. We previously reported improved preclinical efficacy and safety of the recombina...

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Autores principales: Martin Gengenbacher, Alexis Vogelzang, Stefanie Schuerer, Doris Lazar, Peggy Kaiser, Stefan H. E. Kaufmann
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/252aa9bd643b4c78aa5e955af0a00e55
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