Dietary Pyridoxine Controls Efficacy of Vitamin B<sub>6</sub>-Auxotrophic Tuberculosis Vaccine Bacillus Calmette-Guérin Δ<italic toggle="yes">ureC</italic>::<italic toggle="yes">hly</italic> Δ<italic toggle="yes">pdx1</italic> in Mice
ABSTRACT The only tuberculosis (TB) vaccine in use today, bacillus Calmette-Guérin (BCG), provides insufficient protection and can cause adverse events in immunocompromised individuals, such as BCGosis in HIV+ newborns. We previously reported improved preclinical efficacy and safety of the recombina...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2014
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Subjects: | |
Online Access: | https://doaj.org/article/252aa9bd643b4c78aa5e955af0a00e55 |
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