Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP

The Staufen proteins recognize secondary structures in 3’-untranslated regions in mRNA transcripts and induce degradation of these mRNAs with the help of the RNA helicase UPF1. Here the authors report that the nonsense-mediated mRNA decay factor UPF2 mediates the interaction between Stau1 and UPF1 i...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Manjeera Gowravaram, Juliane Schwarz, Sana K. Khilji, Henning Urlaub, Sutapa Chakrabarti
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/254321cfddc94877a3603f84eb782f0d
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!