Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida

Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida

Natural killer (NK) cells has been show to mediate fungi killing via the activating receptor NKp30, but the fungal target for NKp30 is still unclear. Here the authors show, using atomic force microscopy and live cell imaging, that β-1,3-glucan is expressed by Cryptococcus neoformans and Candida albi...

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Autores principales: Shu Shun Li, Henry Ogbomo, Michael K. Mansour, Richard F. Xiang, Lian Szabo, Fay Munro, Priyanka Mukherjee, Roy A. Mariuzza, Matthias Amrein, Jatin M. Vyas, Stephen M. Robbins, Christopher H. Mody
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/2544882c0af34f56b6d9c66dfded2082
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