Decreased levels of bisecting GlcNAc glycoforms of IgG are associated with human longevity.
<h4>Background</h4>Markers for longevity that reflect the health condition and predict healthy aging are extremely scarce. Such markers are, however, valuable in aging research. It has been shown previously that the N-glycosylation pattern of human immunoglobulin G (IgG) is age-dependent...
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Main Authors: | L Renee Ruhaak, Hae-Won Uh, Marian Beekman, Carolien A M Koeleman, Cornelis H Hokke, Rudi G J Westendorp, Manfred Wuhrer, Jeanine J Houwing-Duistermaat, P Eline Slagboom, André M Deelder |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Online Access: | https://doaj.org/article/254679fc5da44461af61d94e662aee7f |
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