Assessment and Management of Diabetic Patients During the COVID-19 Pandemic
Amit K Verma,1 Mirza Masroor Ali Beg,2 Deepti Bhatt,1 Kapil Dev,1 Mohammed A Alsahli,3 Arshad Husain Rahmani,3 Yamini Goyal1 1Medical Biotechnology Lab, Department of Biotechnology, Jamia Millia Islamia, New Delhi, India; 2Department of Biochemistry, Maulana Azad Medical College, New Delhi, India; 3...
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| Formato: | article |
| Lenguaje: | EN |
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Dove Medical Press
2021
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| Acceso en línea: | https://doaj.org/article/254a37be4aba4c66bbe5f839456e0c37 |
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| Sumario: | Amit K Verma,1 Mirza Masroor Ali Beg,2 Deepti Bhatt,1 Kapil Dev,1 Mohammed A Alsahli,3 Arshad Husain Rahmani,3 Yamini Goyal1 1Medical Biotechnology Lab, Department of Biotechnology, Jamia Millia Islamia, New Delhi, India; 2Department of Biochemistry, Maulana Azad Medical College, New Delhi, India; 3Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi ArabiaCorrespondence: Yamini GoyalMedical Biotechnology Lab, Department of Biotechnology, Jamia Millia Islamia, Srinivasa Ramanujan Block, Mujeeb Bagh, New Delhi, 110025, IndiaEmail yamini188673@st.jmi.ac.inAbstract: COVID-19 has become a great challenge across the globe, particularly in developing and densely populated countries, such as India. COVID-19 is extremely infectious and is transmitted via respiratory droplets from infected persons. DM, hypertension, and cardiovascular disease are highly prevalent comorbidities associated with COVID-19. It has been observed that COVID-19 is associated with high blood-glucose levels, mainly in people with type 2 diabetes mellitus (T2DM). Several studies have shown DM to be a significant risk factor affecting the severity of various kinds of infection. Dysregulated immunoresponse found in diabetic patients plays an important role in exacerbating severity. DM is among the comorbidities linked with mortality and morbidity in COVID-19 patients. Chronic conditions like obesity, cardiovascular disorders, and hypertension, together with changed expression of ACE2, dysregulated immunoresponse, and endothelial dysfunction, may put diabetic patients at risk of greater COVID-19 severity. Therefore, it is important to study specific characteristics of COVID-19 in diabetic people and treat these comorbidities along with COVID-19 infection, mainly among old individuals who are already suffering from serious and critical infections. This review will be helpful in understanding the mechanisms involved in COVID-19 and DM, the role of ACE2 in COVID-19 pathogenesis, management of DM, and associated complications in COVID-19 patients.Keywords: COVID-19, diabetes, hypertension, cardiovascular diseases, India |
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