Stromal-driven and Amyloid β-dependent induction of neutrophil extracellular traps modulates tumor growth

The tumor microenvironment is composed of many cell types that crosstalk to modulate local immunity. Here the authors show that Amyloid β proteins from cancer-associated fibroblasts (CAF) induce neutrophil extracellular trap (NET) production by neutrophils, while NET feeds back to activate CAF, ther...

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Autores principales: Hafsa Munir, James O. Jones, Tobias Janowitz, Markus Hoffmann, Maximilien Euler, Carla P. Martins, Sarah J. Welsh, Jacqueline D. Shields
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2556fc9e34b0446f9be86ba29dd43111
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