Hypomethylation of serum blood clot DNA, but not plasma EDTA-blood cell pellet DNA, from vitamin B12-deficient subjects.

Vitamin B12, a co-factor in methyl-group transfer, is important in maintaining DNA (deoxycytidine) methylation. Using two independent assays we examined the effect of vitamin B12-deficiency (plasma vitamin B12<148 pmol/L) on DNA methylation in women of childbearing age. Coagulated blood clot DNA...

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Autores principales: Eoin P Quinlivan, Krista S Crider, Jiang-Hui Zhu, David R Maneval, Ling Hao, Zhu Li, Sonja A Rasmussen, R J Berry, Lynn B Bailey
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/255f519e379d45c695f8d37f9bc94bae
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