Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells
Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells and characterize a role for specific nucleopor...
Guardado en:
Autores principales: | , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/25652c853649470992f3e868f9d71ef1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:25652c853649470992f3e868f9d71ef1 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:25652c853649470992f3e868f9d71ef12021-12-02T15:33:56ZNucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells10.1038/s41467-018-05208-22041-1723https://doaj.org/article/25652c853649470992f3e868f9d71ef12018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05208-2https://doaj.org/toc/2041-1723Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells and characterize a role for specific nucleoporins in mediating Kcnq1ot1 imprinted regulation.Saqib S. SachaniLauren S. LandschootLiyue ZhangCarlee R. WhiteWilliam A. MacDonaldMichael C. GoldingMellissa R. W. MannNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Saqib S. Sachani Lauren S. Landschoot Liyue Zhang Carlee R. White William A. MacDonald Michael C. Golding Mellissa R. W. Mann Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells |
description |
Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells and characterize a role for specific nucleoporins in mediating Kcnq1ot1 imprinted regulation. |
format |
article |
author |
Saqib S. Sachani Lauren S. Landschoot Liyue Zhang Carlee R. White William A. MacDonald Michael C. Golding Mellissa R. W. Mann |
author_facet |
Saqib S. Sachani Lauren S. Landschoot Liyue Zhang Carlee R. White William A. MacDonald Michael C. Golding Mellissa R. W. Mann |
author_sort |
Saqib S. Sachani |
title |
Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells |
title_short |
Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells |
title_full |
Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells |
title_fullStr |
Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells |
title_full_unstemmed |
Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells |
title_sort |
nucleoporin 107, 62 and 153 mediate kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/25652c853649470992f3e868f9d71ef1 |
work_keys_str_mv |
AT saqibssachani nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells AT laurenslandschoot nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells AT liyuezhang nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells AT carleerwhite nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells AT williamamacdonald nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells AT michaelcgolding nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells AT mellissarwmann nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells |
_version_ |
1718386949969936384 |