Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells

Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells and characterize a role for specific nucleopor...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Saqib S. Sachani, Lauren S. Landschoot, Liyue Zhang, Carlee R. White, William A. MacDonald, Michael C. Golding, Mellissa R. W. Mann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/25652c853649470992f3e868f9d71ef1
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:25652c853649470992f3e868f9d71ef1
record_format dspace
spelling oai:doaj.org-article:25652c853649470992f3e868f9d71ef12021-12-02T15:33:56ZNucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells10.1038/s41467-018-05208-22041-1723https://doaj.org/article/25652c853649470992f3e868f9d71ef12018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05208-2https://doaj.org/toc/2041-1723Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells and characterize a role for specific nucleoporins in mediating Kcnq1ot1 imprinted regulation.Saqib S. SachaniLauren S. LandschootLiyue ZhangCarlee R. WhiteWilliam A. MacDonaldMichael C. GoldingMellissa R. W. MannNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Saqib S. Sachani
Lauren S. Landschoot
Liyue Zhang
Carlee R. White
William A. MacDonald
Michael C. Golding
Mellissa R. W. Mann
Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells
description Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells and characterize a role for specific nucleoporins in mediating Kcnq1ot1 imprinted regulation.
format article
author Saqib S. Sachani
Lauren S. Landschoot
Liyue Zhang
Carlee R. White
William A. MacDonald
Michael C. Golding
Mellissa R. W. Mann
author_facet Saqib S. Sachani
Lauren S. Landschoot
Liyue Zhang
Carlee R. White
William A. MacDonald
Michael C. Golding
Mellissa R. W. Mann
author_sort Saqib S. Sachani
title Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells
title_short Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells
title_full Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells
title_fullStr Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells
title_full_unstemmed Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells
title_sort nucleoporin 107, 62 and 153 mediate kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/25652c853649470992f3e868f9d71ef1
work_keys_str_mv AT saqibssachani nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells
AT laurenslandschoot nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells
AT liyuezhang nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells
AT carleerwhite nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells
AT williamamacdonald nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells
AT michaelcgolding nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells
AT mellissarwmann nucleoporin10762and153mediatekcnq1ot1imprinteddomainregulationinextraembryonicendodermstemcells
_version_ 1718386949969936384