Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells

Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells and characterize a role for specific nucleopor...

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Autores principales: Saqib S. Sachani, Lauren S. Landschoot, Liyue Zhang, Carlee R. White, William A. MacDonald, Michael C. Golding, Mellissa R. W. Mann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/25652c853649470992f3e868f9d71ef1
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