Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples

Quick and accurate measurements of specific metabolites are critical to diagnose certain pathological conditions, but quantification methods for relatively low molecular-weight metabolites are limited. Here, the water-soluble pillar[6]arene is used to specifically and quantitatively detect 1-methyln...

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Autores principales:	Masaya Ueno, Takuya Tomita, Hiroshi Arakawa, Takahiro Kakuta, Tada-aki Yamagishi, Jumpei Terakawa, Takiko Daikoku, Shin-ichi Horike, Sha Si, Kenta Kurayoshi, Chiaki Ito, Atsuko Kasahara, Yuko Tadokoro, Masahiko Kobayashi, Tsutomu Fukuwatari, Ikumi Tamai, Atsushi Hirao, Tomoki Ogoshi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/25681a3ee5eb4ebd828c56a3211c1b2c
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spelling	oai:doaj.org-article:25681a3ee5eb4ebd828c56a3211c1b2c2021-12-02T12:30:40ZPillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples10.1038/s42004-020-00430-w2399-3669https://doaj.org/article/25681a3ee5eb4ebd828c56a3211c1b2c2020-12-01T00:00:00Zhttps://doi.org/10.1038/s42004-020-00430-whttps://doaj.org/toc/2399-3669Quick and accurate measurements of specific metabolites are critical to diagnose certain pathological conditions, but quantification methods for relatively low molecular-weight metabolites are limited. Here, the water-soluble pillar[6]arene is used to specifically and quantitatively detect 1-methylnicotinamide in crude urinary samples.Masaya UenoTakuya TomitaHiroshi ArakawaTakahiro KakutaTada-aki YamagishiJumpei TerakawaTakiko DaikokuShin-ichi HorikeSha SiKenta KurayoshiChiaki ItoAtsuko KasaharaYuko TadokoroMasahiko KobayashiTsutomu FukuwatariIkumi TamaiAtsushi HiraoTomoki OgoshiNature PortfolioarticleChemistryQD1-999ENCommunications Chemistry, Vol 3, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Chemistry QD1-999
spellingShingle	Chemistry QD1-999 Masaya Ueno Takuya Tomita Hiroshi Arakawa Takahiro Kakuta Tada-aki Yamagishi Jumpei Terakawa Takiko Daikoku Shin-ichi Horike Sha Si Kenta Kurayoshi Chiaki Ito Atsuko Kasahara Yuko Tadokoro Masahiko Kobayashi Tsutomu Fukuwatari Ikumi Tamai Atsushi Hirao Tomoki Ogoshi Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples
description	Quick and accurate measurements of specific metabolites are critical to diagnose certain pathological conditions, but quantification methods for relatively low molecular-weight metabolites are limited. Here, the water-soluble pillar[6]arene is used to specifically and quantitatively detect 1-methylnicotinamide in crude urinary samples.
format	article
author	Masaya Ueno Takuya Tomita Hiroshi Arakawa Takahiro Kakuta Tada-aki Yamagishi Jumpei Terakawa Takiko Daikoku Shin-ichi Horike Sha Si Kenta Kurayoshi Chiaki Ito Atsuko Kasahara Yuko Tadokoro Masahiko Kobayashi Tsutomu Fukuwatari Ikumi Tamai Atsushi Hirao Tomoki Ogoshi
author_facet	Masaya Ueno Takuya Tomita Hiroshi Arakawa Takahiro Kakuta Tada-aki Yamagishi Jumpei Terakawa Takiko Daikoku Shin-ichi Horike Sha Si Kenta Kurayoshi Chiaki Ito Atsuko Kasahara Yuko Tadokoro Masahiko Kobayashi Tsutomu Fukuwatari Ikumi Tamai Atsushi Hirao Tomoki Ogoshi
author_sort	Masaya Ueno
title	Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples
title_short	Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples
title_full	Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples
title_fullStr	Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples
title_full_unstemmed	Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples
title_sort	pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/25681a3ee5eb4ebd828c56a3211c1b2c
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Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples

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