Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients.

Sera from 25 metastatic breast cancer patients and 25 healthy controls were subjected to affinity chromatography using immobilized galectin-1. Serum from the healthy subjects contained on average 1.2 mg per ml (range 0.7-2.2) galectin-1 binding glycoproteins, whereas serum from the breast cancer pat...

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Main Authors: Michael C Carlsson, Cecilia Cederfur, Viveka Schaar, Crina I A Balog, Adriana Lepur, Franck Touret, Emma Salomonsson, André M Deelder, Mårten Fernö, Håkan Olsson, Manfred Wuhrer, Hakon Leffler
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
R
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Online Access:https://doaj.org/article/256ae61a59fe42d98ad31ef93e5f1837
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