CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits

CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits

CSF-contacting neurons are known to project to locomotor CPGs although their relevance to active locomotion is unclear. Here, the authors show that these cells constitute a mechanosensory organ relying on PKD2L1 channels to detect spinal cord curvature and modulate locomotor frequency in freely movi...

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Autores principales: Urs Lucas Böhm, Andrew Prendergast, Lydia Djenoune, Sophie Nunes Figueiredo, Johanna Gomez, Caleb Stokes, Sonya Kaiser, Maximilliano Suster, Koichi Kawakami, Marine Charpentier, Jean-Paul Concordet, Jean-Paul Rio, Filippo Del Bene, Claire Wyart
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/25791dd165b94a4e9900651c693643a8
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