Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs)
Abstract The interactions of derivatives of lumisterol (L3) and vitamin D3 (D3) with liver X receptors (LXRs) were investigated. Molecular docking using crystal structures of the ligand binding domains (LBDs) of LXRα and β revealed high docking scores for L3 and D3 hydroxymetabolites, similar to tho...
Guardado en:
Autores principales: | Andrzej T. Slominski, Tae-Kang Kim, Shariq Qayyum, Yuwei Song, Zorica Janjetovic, Allen S. W. Oak, Radomir M. Slominski, Chander Raman, Joanna Stefan, Carlos A. Mier-Aguilar, Venkatram Atigadda, David K. Crossman, Andriy Golub, Yaroslav Bilokin, Edith K. Y. Tang, Jake Y. Chen, Robert C. Tuckey, Anton M. Jetten, Yuhua Song |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/25793fb5b8704b48b8b033ea0ef380e3 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways
por: Zorica Janjetovic, et al.
Publicado: (2017) -
Dynamic Autonomous Identification and Intelligent Lighting of Moving Objects with Discomfort Glare Limitation
por: Sebastian Słomiński, et al.
Publicado: (2021) -
Impact of isoflavone genistein on psoriasis in in vivo and in vitro investigations
por: Katarzyna Bocheńska, et al.
Publicado: (2021) -
Comparative Floral and Pollen Micromorphology of <i>Leonurus</i> <i>japonicus</i> and <i>L. macranthus</i> (Lamiaceae)
por: Min-Kyeong Oak, et al.
Publicado: (2021) -
Descenso de la fecundidad y participación laboral femenina en México
por: Mier y Terán, Marta
Publicado: (2014)