Induction of a chromatin boundary in vivo upon insertion of a TAD border.
Mammalian genomes are partitioned into sub-megabase to megabase-sized units of preferential interactions called topologically associating domains or TADs, which are likely important for the proper implementation of gene regulatory processes. These domains provide structural scaffolds for distant cis...
Guardado en:
Autores principales: | Andréa Willemin, Lucille Lopez-Delisle, Christopher Chase Bolt, Marie-Laure Gadolini, Denis Duboule, Eddie Rodriguez-Carballo |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/258973812dc0457fb34148a8b083a2d4 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations
por: Christopher Chase Bolt, et al.
Publicado: (2021) -
A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus
por: A. Rasim Barutcu, et al.
Publicado: (2018) -
M1BP cooperates with CP190 to activate transcription at TAD borders and promote chromatin insulator activity
por: Indira Bag, et al.
Publicado: (2021) -
Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries
por: Yixiao Gong, et al.
Publicado: (2018) -
TAD reorganization: a new mechanism for cell fate determination
por: Zhou Songyang
Publicado: (2021)