Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis
A hallmark of diverticular disease is pouches in the bowel wall which can become infected and inflamed, causing the more severe diverticulitis. Here, the authors report the first genome-wide association study on these interconnected conditions and identifyARHGAP15, COLQ and FAM155Aas novel risk loci...
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Nature Portfolio
2017
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oai:doaj.org-article:258e8dbdaa804b238425c044540087022021-12-02T14:42:19ZSequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis10.1038/ncomms157892041-1723https://doaj.org/article/258e8dbdaa804b238425c044540087022017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15789https://doaj.org/toc/2041-1723A hallmark of diverticular disease is pouches in the bowel wall which can become infected and inflamed, causing the more severe diverticulitis. Here, the authors report the first genome-wide association study on these interconnected conditions and identifyARHGAP15, COLQ and FAM155Aas novel risk loci.Snaevar SigurdssonKristjan F. AlexanderssonPatrick SulemBjarke FeenstraSteinunn GudmundsdottirGisli H. HalldorssonSigurgeir OlafssonAsgeir SigurdssonThorunn RafnarThorgeir ThorgeirssonErik SørensenAndreas Nordholm-CarstensenJakob BurcharthJens AndersenHenrik Stig JørgensenEmma Possfelt-MøllerHenrik UllumGudmar ThorleifssonGisli MassonUnnur ThorsteinsdottirMads MelbyeDaniel F. GudbjartssonTryggvi StefanssonIngileif JonsdottirKari StefanssonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017) |
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| topic |
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Science Q Snaevar Sigurdsson Kristjan F. Alexandersson Patrick Sulem Bjarke Feenstra Steinunn Gudmundsdottir Gisli H. Halldorsson Sigurgeir Olafsson Asgeir Sigurdsson Thorunn Rafnar Thorgeir Thorgeirsson Erik Sørensen Andreas Nordholm-Carstensen Jakob Burcharth Jens Andersen Henrik Stig Jørgensen Emma Possfelt-Møller Henrik Ullum Gudmar Thorleifsson Gisli Masson Unnur Thorsteinsdottir Mads Melbye Daniel F. Gudbjartsson Tryggvi Stefansson Ingileif Jonsdottir Kari Stefansson Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis |
| description |
A hallmark of diverticular disease is pouches in the bowel wall which can become infected and inflamed, causing the more severe diverticulitis. Here, the authors report the first genome-wide association study on these interconnected conditions and identifyARHGAP15, COLQ and FAM155Aas novel risk loci. |
| format |
article |
| author |
Snaevar Sigurdsson Kristjan F. Alexandersson Patrick Sulem Bjarke Feenstra Steinunn Gudmundsdottir Gisli H. Halldorsson Sigurgeir Olafsson Asgeir Sigurdsson Thorunn Rafnar Thorgeir Thorgeirsson Erik Sørensen Andreas Nordholm-Carstensen Jakob Burcharth Jens Andersen Henrik Stig Jørgensen Emma Possfelt-Møller Henrik Ullum Gudmar Thorleifsson Gisli Masson Unnur Thorsteinsdottir Mads Melbye Daniel F. Gudbjartsson Tryggvi Stefansson Ingileif Jonsdottir Kari Stefansson |
| author_facet |
Snaevar Sigurdsson Kristjan F. Alexandersson Patrick Sulem Bjarke Feenstra Steinunn Gudmundsdottir Gisli H. Halldorsson Sigurgeir Olafsson Asgeir Sigurdsson Thorunn Rafnar Thorgeir Thorgeirsson Erik Sørensen Andreas Nordholm-Carstensen Jakob Burcharth Jens Andersen Henrik Stig Jørgensen Emma Possfelt-Møller Henrik Ullum Gudmar Thorleifsson Gisli Masson Unnur Thorsteinsdottir Mads Melbye Daniel F. Gudbjartsson Tryggvi Stefansson Ingileif Jonsdottir Kari Stefansson |
| author_sort |
Snaevar Sigurdsson |
| title |
Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis |
| title_short |
Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis |
| title_full |
Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis |
| title_fullStr |
Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis |
| title_full_unstemmed |
Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis |
| title_sort |
sequence variants in arhgap15, colq and fam155a associate with diverticular disease and diverticulitis |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/258e8dbdaa804b238425c04454008702 |
| work_keys_str_mv |
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