Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells.

Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells.

<h4>Background</h4>Leukotriene D(4) (LTD(4)) belongs to the bioactive lipid group known as eicosanoids and has implications in pathological processes such as inflammation and cancer. Leukotriene D(4) exerts its effects mainly through two different G-protein-coupled receptors, CysLT(1) an...

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Autores principales: Ladan Parhamifar, Wondossen Sime, Yuliana Yudina, Frederik Vilhardt, Matthias Mörgelin, Anita Sjölander
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
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Acceso en línea:https://doaj.org/article/2593142dbc78474f9adb0162f902233c
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