Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients

Characterisation of the human antibody response to SARS-CoV-2 can help the design of serological tests and vaccines. Here, the authors identify two linear epitopes in SARS-CoV-2 spike protein that elicit neutralising antibodies in several patients and could thus be useful for serology and vaccine de...

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Autores principales:	Chek Meng Poh, Guillaume Carissimo, Bei Wang, Siti Naqiah Amrun, Cheryl Yi-Pin Lee, Rhonda Sin-Ling Chee, Siew-Wai Fong, Nicholas Kim-Wah Yeo, Wen-Hsin Lee, Anthony Torres-Ruesta, Yee-Sin Leo, Mark I-Cheng Chen, Seow-Yen Tan, Louis Yi Ann Chai, Shirin Kalimuddin, Shirley Seah Gek Kheng, Siew-Yee Thien, Barnaby Edward Young, David C. Lye, Brendon John Hanson, Cheng-I Wang, Laurent Renia, Lisa F. P. Ng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/259727a9ff5945239e9dc10420f01ef8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:259727a9ff5945239e9dc10420f01ef82021-12-02T17:51:27ZTwo linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients10.1038/s41467-020-16638-22041-1723https://doaj.org/article/259727a9ff5945239e9dc10420f01ef82020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16638-2https://doaj.org/toc/2041-1723Characterisation of the human antibody response to SARS-CoV-2 can help the design of serological tests and vaccines. Here, the authors identify two linear epitopes in SARS-CoV-2 spike protein that elicit neutralising antibodies in several patients and could thus be useful for serology and vaccine development.Chek Meng PohGuillaume CarissimoBei WangSiti Naqiah AmrunCheryl Yi-Pin LeeRhonda Sin-Ling CheeSiew-Wai FongNicholas Kim-Wah YeoWen-Hsin LeeAnthony Torres-RuestaYee-Sin LeoMark I-Cheng ChenSeow-Yen TanLouis Yi Ann ChaiShirin KalimuddinShirley Seah Gek KhengSiew-Yee ThienBarnaby Edward YoungDavid C. LyeBrendon John HansonCheng-I WangLaurent ReniaLisa F. P. NgNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chek Meng Poh Guillaume Carissimo Bei Wang Siti Naqiah Amrun Cheryl Yi-Pin Lee Rhonda Sin-Ling Chee Siew-Wai Fong Nicholas Kim-Wah Yeo Wen-Hsin Lee Anthony Torres-Ruesta Yee-Sin Leo Mark I-Cheng Chen Seow-Yen Tan Louis Yi Ann Chai Shirin Kalimuddin Shirley Seah Gek Kheng Siew-Yee Thien Barnaby Edward Young David C. Lye Brendon John Hanson Cheng-I Wang Laurent Renia Lisa F. P. Ng Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients
description	Characterisation of the human antibody response to SARS-CoV-2 can help the design of serological tests and vaccines. Here, the authors identify two linear epitopes in SARS-CoV-2 spike protein that elicit neutralising antibodies in several patients and could thus be useful for serology and vaccine development.
format	article
author	Chek Meng Poh Guillaume Carissimo Bei Wang Siti Naqiah Amrun Cheryl Yi-Pin Lee Rhonda Sin-Ling Chee Siew-Wai Fong Nicholas Kim-Wah Yeo Wen-Hsin Lee Anthony Torres-Ruesta Yee-Sin Leo Mark I-Cheng Chen Seow-Yen Tan Louis Yi Ann Chai Shirin Kalimuddin Shirley Seah Gek Kheng Siew-Yee Thien Barnaby Edward Young David C. Lye Brendon John Hanson Cheng-I Wang Laurent Renia Lisa F. P. Ng
author_facet	Chek Meng Poh Guillaume Carissimo Bei Wang Siti Naqiah Amrun Cheryl Yi-Pin Lee Rhonda Sin-Ling Chee Siew-Wai Fong Nicholas Kim-Wah Yeo Wen-Hsin Lee Anthony Torres-Ruesta Yee-Sin Leo Mark I-Cheng Chen Seow-Yen Tan Louis Yi Ann Chai Shirin Kalimuddin Shirley Seah Gek Kheng Siew-Yee Thien Barnaby Edward Young David C. Lye Brendon John Hanson Cheng-I Wang Laurent Renia Lisa F. P. Ng
author_sort	Chek Meng Poh
title	Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients
title_short	Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients
title_full	Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients
title_fullStr	Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients
title_full_unstemmed	Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients
title_sort	two linear epitopes on the sars-cov-2 spike protein that elicit neutralising antibodies in covid-19 patients
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/259727a9ff5945239e9dc10420f01ef8
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Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients

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