Biomarkers Utility: At the Borderline between Cardiology and Neurology

Biomarkers are important diagnostic and prognostic tools as they provide results in a short time while still being an inexpensive, reproducible and accessible method. Their well-known benefits have placed them at the forefront of research in recent years, with new and innovative discoveries being im...

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Autores principales:	Adriana Ion, Celina Stafie, Ovidiu Mitu, Cosmina Elena Ciobanu, Dan Iliescu Halitchi, Alexandru Dan Costache, Cezara Bobric, Roxana Troase, Ivona Mitu, Bogdan Huzum, Stefania Teodora Duca, Irina Iuliana Costache
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	biomarkers cardiology neurology troponin cardiovascular diseases BNP Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/259c155f500b430eab5211a90846d72d
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spelling	oai:doaj.org-article:259c155f500b430eab5211a90846d72d2021-11-25T18:00:14ZBiomarkers Utility: At the Borderline between Cardiology and Neurology10.3390/jcdd81101392308-3425https://doaj.org/article/259c155f500b430eab5211a90846d72d2021-10-01T00:00:00Zhttps://www.mdpi.com/2308-3425/8/11/139https://doaj.org/toc/2308-3425Biomarkers are important diagnostic and prognostic tools as they provide results in a short time while still being an inexpensive, reproducible and accessible method. Their well-known benefits have placed them at the forefront of research in recent years, with new and innovative discoveries being implemented. Cardiovascular and neurological diseases often share common risk factors and pathological pathways which may play an important role in the use and interpretation of biomarkers’ values. Among the biomarkers used extensively in clinical practice in cardiology, hs-TroponinT, CK-MB and NTproBNP have been shown to be strongly influenced by multiple neurological conditions. Newer ones such as galectin-3, lysophosphatidylcholine, copeptin, sST2, S100B, myeloperoxidase and GDF-15 have been extensively studied in recent years as alternatives with an increased sensitivity for cardiovascular diseases, but also with significant results in the field of neurology. Thus, given their low specificity, the values interpretation must be correlated with the clinical judgment and other available investigations.Adriana IonCelina StafieOvidiu MituCosmina Elena CiobanuDan Iliescu HalitchiAlexandru Dan CostacheCezara BobricRoxana TroaseIvona MituBogdan HuzumStefania Teodora DucaIrina Iuliana CostacheMDPI AGarticlebiomarkerscardiologyneurologytroponincardiovascular diseasesBNPDiseases of the circulatory (Cardiovascular) systemRC666-701ENJournal of Cardiovascular Development and Disease, Vol 8, Iss 139, p 139 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	biomarkers cardiology neurology troponin cardiovascular diseases BNP Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	biomarkers cardiology neurology troponin cardiovascular diseases BNP Diseases of the circulatory (Cardiovascular) system RC666-701 Adriana Ion Celina Stafie Ovidiu Mitu Cosmina Elena Ciobanu Dan Iliescu Halitchi Alexandru Dan Costache Cezara Bobric Roxana Troase Ivona Mitu Bogdan Huzum Stefania Teodora Duca Irina Iuliana Costache Biomarkers Utility: At the Borderline between Cardiology and Neurology
description	Biomarkers are important diagnostic and prognostic tools as they provide results in a short time while still being an inexpensive, reproducible and accessible method. Their well-known benefits have placed them at the forefront of research in recent years, with new and innovative discoveries being implemented. Cardiovascular and neurological diseases often share common risk factors and pathological pathways which may play an important role in the use and interpretation of biomarkers’ values. Among the biomarkers used extensively in clinical practice in cardiology, hs-TroponinT, CK-MB and NTproBNP have been shown to be strongly influenced by multiple neurological conditions. Newer ones such as galectin-3, lysophosphatidylcholine, copeptin, sST2, S100B, myeloperoxidase and GDF-15 have been extensively studied in recent years as alternatives with an increased sensitivity for cardiovascular diseases, but also with significant results in the field of neurology. Thus, given their low specificity, the values interpretation must be correlated with the clinical judgment and other available investigations.
format	article
author	Adriana Ion Celina Stafie Ovidiu Mitu Cosmina Elena Ciobanu Dan Iliescu Halitchi Alexandru Dan Costache Cezara Bobric Roxana Troase Ivona Mitu Bogdan Huzum Stefania Teodora Duca Irina Iuliana Costache
author_facet	Adriana Ion Celina Stafie Ovidiu Mitu Cosmina Elena Ciobanu Dan Iliescu Halitchi Alexandru Dan Costache Cezara Bobric Roxana Troase Ivona Mitu Bogdan Huzum Stefania Teodora Duca Irina Iuliana Costache
author_sort	Adriana Ion
title	Biomarkers Utility: At the Borderline between Cardiology and Neurology
title_short	Biomarkers Utility: At the Borderline between Cardiology and Neurology
title_full	Biomarkers Utility: At the Borderline between Cardiology and Neurology
title_fullStr	Biomarkers Utility: At the Borderline between Cardiology and Neurology
title_full_unstemmed	Biomarkers Utility: At the Borderline between Cardiology and Neurology
title_sort	biomarkers utility: at the borderline between cardiology and neurology
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/259c155f500b430eab5211a90846d72d
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Biomarkers Utility: At the Borderline between Cardiology and Neurology

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