Induction of murine macrophage M2 polarization by cigarette smoke extract via the JAK2/STAT3 pathway.

Cigarette smoking is a major pathogenic factor in lung cancer. Macrophages play an important role in host defense and adaptive immunity. These cells display diverse phenotypes for performing different functions. M2 type macrophages usually exhibit immunosuppressive and tumor-promoting characteristic...

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Auteurs principaux: Fengjiao Yuan, Xiao Fu, Hengfei Shi, Guopu Chen, Ping Dong, Weiyun Zhang
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/25af7d2971c44df9a4142b58e120399d
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