Circulatory and prostatic tissue lipidomic profiles shifts after high-dose atorvastatin use in men with prostate cancer

Abstract Prostate cancer patients using cholesterol-lowering statins have 30% lower risk of prostate cancer death compared to non-users. The effect is attributed to the inhibition of the mevalonate pathway in prostate cancer cells. Moreover, statin use causes lipoprotein metabolism changes in the se...

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Autores principales: Paavo Raittinen, Kati Niemistö, Erika Pennanen, Heimo Syvälä, Seppo Auriola, Jarno Riikonen, Terho Lehtimäki, Pauliina Ilmonen, Teemu Murtola
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/25b99540e9c54e4abc8a9297592afb94
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