Nanotechnology-based drug delivery systems for treatment of oral cancer: a review

Giovana Calixto, Jéssica Bernegossi, Bruno Fonseca-Santos, Marlus Chorilli School of Pharmaceutical Sciences, Department of Drugs and Pharmaceuticals, São Paulo State University (UNESP), São Paulo, Brazil Abstract: Oral cancer (oral cavity and oropharynx) is a com...

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Autores principales:	Calixto G, Bernegossi J, Fonseca-Santos B, Chorilli M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/25bc4f4cf3ed40348833c86d08b5d973
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spelling	oai:doaj.org-article:25bc4f4cf3ed40348833c86d08b5d9732021-12-02T00:43:21ZNanotechnology-based drug delivery systems for treatment of oral cancer: a review1178-2013https://doaj.org/article/25bc4f4cf3ed40348833c86d08b5d9732014-08-01T00:00:00Zhttp://www.dovepress.com/nanotechnology-based-drug-delivery-systems-for-treatment-of-oral-cance-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013 Giovana Calixto, Jéssica Bernegossi, Bruno Fonseca-Santos, Marlus Chorilli School of Pharmaceutical Sciences, Department of Drugs and Pharmaceuticals, São Paulo State University (UNESP), São Paulo, Brazil Abstract: Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, have improved over the past few decades; however, they remain far from optimal. Currently, cancer research is focused on improving cancer diagnosis and treatment methods (oral cavity and oropharynx) nanotechnology, which involves the design, characterization, production, and application of nanoscale drug delivery systems. In medicine, nanotechnologies, such as polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, gold nanoparticles, hydrogels, cyclodextrin complexes, and liquid crystals, are promising tools for diagnostic probes and therapeutic devices. The objective of this study is to present a systematic review of nanotechnology-based drug delivery systems for oral cancers. Keywords: targeted delivery, oral squamous cell carcinoma, oral cancer treatmentCalixto GBernegossi JFonseca-Santos BChorilli MDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 3719-3735 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Calixto G Bernegossi J Fonseca-Santos B Chorilli M Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
description	Giovana Calixto, Jéssica Bernegossi, Bruno Fonseca-Santos, Marlus Chorilli School of Pharmaceutical Sciences, Department of Drugs and Pharmaceuticals, São Paulo State University (UNESP), São Paulo, Brazil Abstract: Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, have improved over the past few decades; however, they remain far from optimal. Currently, cancer research is focused on improving cancer diagnosis and treatment methods (oral cavity and oropharynx) nanotechnology, which involves the design, characterization, production, and application of nanoscale drug delivery systems. In medicine, nanotechnologies, such as polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, gold nanoparticles, hydrogels, cyclodextrin complexes, and liquid crystals, are promising tools for diagnostic probes and therapeutic devices. The objective of this study is to present a systematic review of nanotechnology-based drug delivery systems for oral cancers. Keywords: targeted delivery, oral squamous cell carcinoma, oral cancer treatment
format	article
author	Calixto G Bernegossi J Fonseca-Santos B Chorilli M
author_facet	Calixto G Bernegossi J Fonseca-Santos B Chorilli M
author_sort	Calixto G
title	Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
title_short	Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
title_full	Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
title_fullStr	Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
title_full_unstemmed	Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
title_sort	nanotechnology-based drug delivery systems for treatment of oral cancer: a review
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/25bc4f4cf3ed40348833c86d08b5d973
work_keys_str_mv	AT calixtog nanotechnologybaseddrugdeliverysystemsfortreatmentoforalcancerareview AT bernegossij nanotechnologybaseddrugdeliverysystemsfortreatmentoforalcancerareview AT fonsecasantosb nanotechnologybaseddrugdeliverysystemsfortreatmentoforalcancerareview AT chorillim nanotechnologybaseddrugdeliverysystemsfortreatmentoforalcancerareview
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Nanotechnology-based drug delivery systems for treatment of oral cancer: a review

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