Generation of a conditional transgenic mouse model expressing human Phospholipase A2 Receptor 1

Generation of a conditional transgenic mouse model expressing human Phospholipase A2 Receptor 1

Abstract The Phospholipase A2 Receptor 1 (PLA2R1) was first identified for its ability to bind some secreted PLA2s (sPLA2s). It belongs to the C-type lectin superfamily and it binds different types of proteins. It is likely a multifunctional protein that plays a role i) in inflammation and inflammat...

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Autores principales: Sara Jaber, Delphine Goehrig, Philippe Bertolino, Amélie Massemin, Franck Bihl, Joëlle Chabry, Gérard Lambeau, David Vindrieux, David Bernard
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/25d2faad67014d5f9762d7d3ad7875d3
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