Heritable DNA methylation marks associated with susceptibility to breast cancer
DNA methylation is associated with breast cancer risk. Here the authors measure DNA methylation in the blood of individuals from 25 Australian families with multiple cases of breast cancer but not known mutations associated with breast cancer risk to identify possible heritable methylation markers.
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Nature Portfolio
2018
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oai:doaj.org-article:25d88abacdcf4337989301d37acb1ebe2021-12-02T16:56:39ZHeritable DNA methylation marks associated with susceptibility to breast cancer10.1038/s41467-018-03058-62041-1723https://doaj.org/article/25d88abacdcf4337989301d37acb1ebe2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03058-6https://doaj.org/toc/2041-1723DNA methylation is associated with breast cancer risk. Here the authors measure DNA methylation in the blood of individuals from 25 Australian families with multiple cases of breast cancer but not known mutations associated with breast cancer risk to identify possible heritable methylation markers.Jihoon E. JooJames G. DowtyRoger L. MilneEe Ming WongPierre-Antoine DuguéDallas EnglishJohn L. HopperDavid E. GoldgarGraham G. GilesMelissa C. SoutheykConFabNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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EN |
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Science Q Jihoon E. Joo James G. Dowty Roger L. Milne Ee Ming Wong Pierre-Antoine Dugué Dallas English John L. Hopper David E. Goldgar Graham G. Giles Melissa C. Southey kConFab Heritable DNA methylation marks associated with susceptibility to breast cancer |
description |
DNA methylation is associated with breast cancer risk. Here the authors measure DNA methylation in the blood of individuals from 25 Australian families with multiple cases of breast cancer but not known mutations associated with breast cancer risk to identify possible heritable methylation markers. |
format |
article |
author |
Jihoon E. Joo James G. Dowty Roger L. Milne Ee Ming Wong Pierre-Antoine Dugué Dallas English John L. Hopper David E. Goldgar Graham G. Giles Melissa C. Southey kConFab |
author_facet |
Jihoon E. Joo James G. Dowty Roger L. Milne Ee Ming Wong Pierre-Antoine Dugué Dallas English John L. Hopper David E. Goldgar Graham G. Giles Melissa C. Southey kConFab |
author_sort |
Jihoon E. Joo |
title |
Heritable DNA methylation marks associated with susceptibility to breast cancer |
title_short |
Heritable DNA methylation marks associated with susceptibility to breast cancer |
title_full |
Heritable DNA methylation marks associated with susceptibility to breast cancer |
title_fullStr |
Heritable DNA methylation marks associated with susceptibility to breast cancer |
title_full_unstemmed |
Heritable DNA methylation marks associated with susceptibility to breast cancer |
title_sort |
heritable dna methylation marks associated with susceptibility to breast cancer |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/25d88abacdcf4337989301d37acb1ebe |
work_keys_str_mv |
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