Heritable DNA methylation marks associated with susceptibility to breast cancer

DNA methylation is associated with breast cancer risk. Here the authors measure DNA methylation in the blood of individuals from 25 Australian families with multiple cases of breast cancer but not known mutations associated with breast cancer risk to identify possible heritable methylation markers.

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Autores principales: Jihoon E. Joo, James G. Dowty, Roger L. Milne, Ee Ming Wong, Pierre-Antoine Dugué, Dallas English, John L. Hopper, David E. Goldgar, Graham G. Giles, Melissa C. Southey, kConFab
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/25d88abacdcf4337989301d37acb1ebe
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spelling oai:doaj.org-article:25d88abacdcf4337989301d37acb1ebe2021-12-02T16:56:39ZHeritable DNA methylation marks associated with susceptibility to breast cancer10.1038/s41467-018-03058-62041-1723https://doaj.org/article/25d88abacdcf4337989301d37acb1ebe2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03058-6https://doaj.org/toc/2041-1723DNA methylation is associated with breast cancer risk. Here the authors measure DNA methylation in the blood of individuals from 25 Australian families with multiple cases of breast cancer but not known mutations associated with breast cancer risk to identify possible heritable methylation markers.Jihoon E. JooJames G. DowtyRoger L. MilneEe Ming WongPierre-Antoine DuguéDallas EnglishJohn L. HopperDavid E. GoldgarGraham G. GilesMelissa C. SoutheykConFabNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jihoon E. Joo
James G. Dowty
Roger L. Milne
Ee Ming Wong
Pierre-Antoine Dugué
Dallas English
John L. Hopper
David E. Goldgar
Graham G. Giles
Melissa C. Southey
kConFab
Heritable DNA methylation marks associated with susceptibility to breast cancer
description DNA methylation is associated with breast cancer risk. Here the authors measure DNA methylation in the blood of individuals from 25 Australian families with multiple cases of breast cancer but not known mutations associated with breast cancer risk to identify possible heritable methylation markers.
format article
author Jihoon E. Joo
James G. Dowty
Roger L. Milne
Ee Ming Wong
Pierre-Antoine Dugué
Dallas English
John L. Hopper
David E. Goldgar
Graham G. Giles
Melissa C. Southey
kConFab
author_facet Jihoon E. Joo
James G. Dowty
Roger L. Milne
Ee Ming Wong
Pierre-Antoine Dugué
Dallas English
John L. Hopper
David E. Goldgar
Graham G. Giles
Melissa C. Southey
kConFab
author_sort Jihoon E. Joo
title Heritable DNA methylation marks associated with susceptibility to breast cancer
title_short Heritable DNA methylation marks associated with susceptibility to breast cancer
title_full Heritable DNA methylation marks associated with susceptibility to breast cancer
title_fullStr Heritable DNA methylation marks associated with susceptibility to breast cancer
title_full_unstemmed Heritable DNA methylation marks associated with susceptibility to breast cancer
title_sort heritable dna methylation marks associated with susceptibility to breast cancer
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/25d88abacdcf4337989301d37acb1ebe
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