Making muscle elastic: the structural basis of myomesin stretching.

Skeletal and cardiac muscles are remarkable biological machines that support and move our bodies and power the rhythmic work of our lungs and hearts. As well as producing active contractile force, muscles are also passively elastic, which is essential to their performance. The origins of both active...

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Autores principales: Larissa Tskhovrebova, John Trinick
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/25ea5affcb1248ae96c22da3b4abc05c
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spelling oai:doaj.org-article:25ea5affcb1248ae96c22da3b4abc05c2021-11-18T05:36:46ZMaking muscle elastic: the structural basis of myomesin stretching.1544-91731545-788510.1371/journal.pbio.1001264https://doaj.org/article/25ea5affcb1248ae96c22da3b4abc05c2012-02-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22347814/?tool=EBIhttps://doaj.org/toc/1544-9173https://doaj.org/toc/1545-7885Skeletal and cardiac muscles are remarkable biological machines that support and move our bodies and power the rhythmic work of our lungs and hearts. As well as producing active contractile force, muscles are also passively elastic, which is essential to their performance. The origins of both active contractile and passive elastic forces can be traced to the individual proteins that make up the highly ordered structure of muscle. In this Primer, we describe the organization of sarcomeres--the structural units that produce contraction--and the nature of the proteins that make muscle elastic. In particular, we focus on an elastic protein called myomesin, whose novel modular architecture helps explain elasticity.Larissa TskhovrebovaJohn TrinickPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Biology, Vol 10, Iss 2, p e1001264 (2012)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Larissa Tskhovrebova
John Trinick
Making muscle elastic: the structural basis of myomesin stretching.
description Skeletal and cardiac muscles are remarkable biological machines that support and move our bodies and power the rhythmic work of our lungs and hearts. As well as producing active contractile force, muscles are also passively elastic, which is essential to their performance. The origins of both active contractile and passive elastic forces can be traced to the individual proteins that make up the highly ordered structure of muscle. In this Primer, we describe the organization of sarcomeres--the structural units that produce contraction--and the nature of the proteins that make muscle elastic. In particular, we focus on an elastic protein called myomesin, whose novel modular architecture helps explain elasticity.
format article
author Larissa Tskhovrebova
John Trinick
author_facet Larissa Tskhovrebova
John Trinick
author_sort Larissa Tskhovrebova
title Making muscle elastic: the structural basis of myomesin stretching.
title_short Making muscle elastic: the structural basis of myomesin stretching.
title_full Making muscle elastic: the structural basis of myomesin stretching.
title_fullStr Making muscle elastic: the structural basis of myomesin stretching.
title_full_unstemmed Making muscle elastic: the structural basis of myomesin stretching.
title_sort making muscle elastic: the structural basis of myomesin stretching.
publisher Public Library of Science (PLoS)
publishDate 2012
url https://doaj.org/article/25ea5affcb1248ae96c22da3b4abc05c
work_keys_str_mv AT larissatskhovrebova makingmuscleelasticthestructuralbasisofmyomesinstretching
AT johntrinick makingmuscleelasticthestructuralbasisofmyomesinstretching
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