Making muscle elastic: the structural basis of myomesin stretching.

Skeletal and cardiac muscles are remarkable biological machines that support and move our bodies and power the rhythmic work of our lungs and hearts. As well as producing active contractile force, muscles are also passively elastic, which is essential to their performance. The origins of both active...

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Auteurs principaux:	Larissa Tskhovrebova, John Trinick
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2012
Sujets:	Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/25ea5affcb1248ae96c22da3b4abc05c
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spelling	oai:doaj.org-article:25ea5affcb1248ae96c22da3b4abc05c2021-11-18T05:36:46ZMaking muscle elastic: the structural basis of myomesin stretching.1544-91731545-788510.1371/journal.pbio.1001264https://doaj.org/article/25ea5affcb1248ae96c22da3b4abc05c2012-02-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22347814/?tool=EBIhttps://doaj.org/toc/1544-9173https://doaj.org/toc/1545-7885Skeletal and cardiac muscles are remarkable biological machines that support and move our bodies and power the rhythmic work of our lungs and hearts. As well as producing active contractile force, muscles are also passively elastic, which is essential to their performance. The origins of both active contractile and passive elastic forces can be traced to the individual proteins that make up the highly ordered structure of muscle. In this Primer, we describe the organization of sarcomeres--the structural units that produce contraction--and the nature of the proteins that make muscle elastic. In particular, we focus on an elastic protein called myomesin, whose novel modular architecture helps explain elasticity.Larissa TskhovrebovaJohn TrinickPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Biology, Vol 10, Iss 2, p e1001264 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Larissa Tskhovrebova John Trinick Making muscle elastic: the structural basis of myomesin stretching.
description	Skeletal and cardiac muscles are remarkable biological machines that support and move our bodies and power the rhythmic work of our lungs and hearts. As well as producing active contractile force, muscles are also passively elastic, which is essential to their performance. The origins of both active contractile and passive elastic forces can be traced to the individual proteins that make up the highly ordered structure of muscle. In this Primer, we describe the organization of sarcomeres--the structural units that produce contraction--and the nature of the proteins that make muscle elastic. In particular, we focus on an elastic protein called myomesin, whose novel modular architecture helps explain elasticity.
format	article
author	Larissa Tskhovrebova John Trinick
author_facet	Larissa Tskhovrebova John Trinick
author_sort	Larissa Tskhovrebova
title	Making muscle elastic: the structural basis of myomesin stretching.
title_short	Making muscle elastic: the structural basis of myomesin stretching.
title_full	Making muscle elastic: the structural basis of myomesin stretching.
title_fullStr	Making muscle elastic: the structural basis of myomesin stretching.
title_full_unstemmed	Making muscle elastic: the structural basis of myomesin stretching.
title_sort	making muscle elastic: the structural basis of myomesin stretching.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/25ea5affcb1248ae96c22da3b4abc05c
work_keys_str_mv	AT larissatskhovrebova makingmuscleelasticthestructuralbasisofmyomesinstretching AT johntrinick makingmuscleelasticthestructuralbasisofmyomesinstretching
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Making muscle elastic: the structural basis of myomesin stretching.

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