A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection

A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection

Class F receptors are therapeutic targets in human disease and understanding their structural changes during receptor activation may provide important pharmacological insight. Here, the authors combine computational and experimental methods to identify a molecular switch in TM6/7 of Class F receptor...

Full description

Saved in:
Bibliographic Details
Main Authors: Shane C. Wright, Paweł Kozielewicz, Maria Kowalski-Jahn, Julian Petersen, Carl-Fredrik Bowin, Greg Slodkowicz, Maria Marti-Solano, David Rodríguez, Belma Hot, Najeah Okashah, Katerina Strakova, Jana Valnohova, M. Madan Babu, Nevin A. Lambert, Jens Carlsson, Gunnar Schulte
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Science
Q
Online Access:https://doaj.org/article/25eb2e5a80d940629421bb3eaf96fb01
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/25eb2e5a80d940629421bb3eaf96fb01

Similar Items