mTORC1 regulates apoptosis and cell proliferation in pterygium via targeting autophagy and FGFR3
Abstract Pterygium is one of the most common ocular surface diseases. During the initiation of pterygium, resting epithelial cells are activated and exhibit aberrant apoptosis and cell proliferation. Mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth, cell proli...
Saved in:
Main Authors: | Yanli Liu, Hanchun Xu, Meixia An |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/25f58fa1c0224c2f824b78ace5aefa25 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Leucine regulates autophagy via acetylation of the mTORC1 component raptor
by: Sung Min Son, et al.
Published: (2020) -
mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
by: Xiaolei Ding, et al.
Published: (2016) -
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
by: Morris E Feldman, et al.
Published: (2009) -
CIB2 regulates mTORC1 signaling and is essential for autophagy and visual function
by: Saumil Sethna, et al.
Published: (2021) -
mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation
by: Bo Yan, et al.
Published: (2016)