mTORC1 regulates apoptosis and cell proliferation in pterygium via targeting autophagy and FGFR3
Abstract Pterygium is one of the most common ocular surface diseases. During the initiation of pterygium, resting epithelial cells are activated and exhibit aberrant apoptosis and cell proliferation. Mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth, cell proli...
Enregistré dans:
Auteurs principaux: | Yanli Liu, Hanchun Xu, Meixia An |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/25f58fa1c0224c2f824b78ace5aefa25 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Leucine regulates autophagy via acetylation of the mTORC1 component raptor
par: Sung Min Son, et autres
Publié: (2020) -
mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
par: Xiaolei Ding, et autres
Publié: (2016) -
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
par: Morris E Feldman, et autres
Publié: (2009) -
CIB2 regulates mTORC1 signaling and is essential for autophagy and visual function
par: Saumil Sethna, et autres
Publié: (2021) -
mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation
par: Bo Yan, et autres
Publié: (2016)