Factors Related to Severity of Diabetic Foot Ulcer: A Systematic Review

Milad Jalilian,1 Pegah Ahmadi Sarbarzeh,1 Sajad Oubari2 1Nursing Department, Nursing and Midwifery School, Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran; 2Laboratory Department, Paramedical School, Student Research Committee, Kermanshah University of Medical...

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Autores principales: Jalilian M, Ahmadi Sarbarzeh P, Oubari S
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Publicado: Dove Medical Press 2020
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spelling oai:doaj.org-article:25f74609cd944fb89ee0b1dedeaebe6e2021-12-02T09:14:05ZFactors Related to Severity of Diabetic Foot Ulcer: A Systematic Review1178-7007https://doaj.org/article/25f74609cd944fb89ee0b1dedeaebe6e2020-05-01T00:00:00Zhttps://www.dovepress.com/factors-related-to-severity-of-diabetic-foot-ulcer-a-systematic-review-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Milad Jalilian,1 Pegah Ahmadi Sarbarzeh,1 Sajad Oubari2 1Nursing Department, Nursing and Midwifery School, Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran; 2Laboratory Department, Paramedical School, Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, IranCorrespondence: Milad Jalilian Tel +989187931047Email milladj1994@gmail.comBackground: Diabetic foot ulcer (DFU) is one of the diabetes complications. DFU can be the cause of a high rate of amputation, health-care costs and even death, and this condition occurs in the severity status of DFU. Severity of DFU is the cause of expensive complication incidence. Understanding the factors affecting it can help preventive functions. Adequate evidence for this problem is necessary. The aim of this systematic review is to summarize evidence on severity of diabetic foot ulcer.Methods: A literature search was undertaken in Scopus, PubMed, Elsevier, MEDLINE, Embase, UpToDate and Google Scholar. Observational studies that assessed severity of DFU were included. The data extraction and assessment are on the basis of PRISMA.Results: Seven studies were assessed and 25 factors that affect severity of DFU are reported in the studies. The most used score for an estimate of severity was the Wagner scale (n=5). The majority of patients were in G1 and G2 stages (67.5%; basis of Wagner) or have a superficial ulcer (62.84%) on the basis of the Texas Diabetic Wound Classification System. The main factors include high BMI, smoking, lack of diabetes control, type of diabetes treatment and older age. In addition, there were other factors that affect severity of DFU such as vascular complications, bacteria isolated, marital status, gender, high levels of cholesterol and triglycerides. Also, life location, type 2 diabetes, genotype, addiction, long-time DFU and delay to refer patients were other factors.Conclusion: Twenty-five factors were reported. The majority of these factors related to life-style and can be prevented by self-care functions. The effect of these factors needs further study and the further studies must be better in quality.Keywords: diabetes, diabetic foot ulcer, severityJalilian MAhmadi Sarbarzeh POubari SDove Medical Pressarticlediabetesdiabetic foot ulcerseveritySpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 13, Pp 1835-1842 (2020)
institution DOAJ
collection DOAJ
language EN
topic diabetes
diabetic foot ulcer
severity
Specialties of internal medicine
RC581-951
spellingShingle diabetes
diabetic foot ulcer
severity
Specialties of internal medicine
RC581-951
Jalilian M
Ahmadi Sarbarzeh P
Oubari S
Factors Related to Severity of Diabetic Foot Ulcer: A Systematic Review
description Milad Jalilian,1 Pegah Ahmadi Sarbarzeh,1 Sajad Oubari2 1Nursing Department, Nursing and Midwifery School, Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran; 2Laboratory Department, Paramedical School, Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, IranCorrespondence: Milad Jalilian Tel +989187931047Email milladj1994@gmail.comBackground: Diabetic foot ulcer (DFU) is one of the diabetes complications. DFU can be the cause of a high rate of amputation, health-care costs and even death, and this condition occurs in the severity status of DFU. Severity of DFU is the cause of expensive complication incidence. Understanding the factors affecting it can help preventive functions. Adequate evidence for this problem is necessary. The aim of this systematic review is to summarize evidence on severity of diabetic foot ulcer.Methods: A literature search was undertaken in Scopus, PubMed, Elsevier, MEDLINE, Embase, UpToDate and Google Scholar. Observational studies that assessed severity of DFU were included. The data extraction and assessment are on the basis of PRISMA.Results: Seven studies were assessed and 25 factors that affect severity of DFU are reported in the studies. The most used score for an estimate of severity was the Wagner scale (n=5). The majority of patients were in G1 and G2 stages (67.5%; basis of Wagner) or have a superficial ulcer (62.84%) on the basis of the Texas Diabetic Wound Classification System. The main factors include high BMI, smoking, lack of diabetes control, type of diabetes treatment and older age. In addition, there were other factors that affect severity of DFU such as vascular complications, bacteria isolated, marital status, gender, high levels of cholesterol and triglycerides. Also, life location, type 2 diabetes, genotype, addiction, long-time DFU and delay to refer patients were other factors.Conclusion: Twenty-five factors were reported. The majority of these factors related to life-style and can be prevented by self-care functions. The effect of these factors needs further study and the further studies must be better in quality.Keywords: diabetes, diabetic foot ulcer, severity
format article
author Jalilian M
Ahmadi Sarbarzeh P
Oubari S
author_facet Jalilian M
Ahmadi Sarbarzeh P
Oubari S
author_sort Jalilian M
title Factors Related to Severity of Diabetic Foot Ulcer: A Systematic Review
title_short Factors Related to Severity of Diabetic Foot Ulcer: A Systematic Review
title_full Factors Related to Severity of Diabetic Foot Ulcer: A Systematic Review
title_fullStr Factors Related to Severity of Diabetic Foot Ulcer: A Systematic Review
title_full_unstemmed Factors Related to Severity of Diabetic Foot Ulcer: A Systematic Review
title_sort factors related to severity of diabetic foot ulcer: a systematic review
publisher Dove Medical Press
publishDate 2020
url https://doaj.org/article/25f74609cd944fb89ee0b1dedeaebe6e
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