Construction of China national newborn growth standards based on a large low-risk sample

Abstract Most published newborn growth references are based on conventional monitoring data that usually included both low- and high-risk pregnancies. We sought to develop a set of neonatal growth standards constructed from only a large sample of low-risk pregnancies. A total of 24,375 naturally con...

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Autores principales:	Xin-Nan Zong, Hui Li, Ya-Qin Zhang, Hua-Hong Wu, Geng-Li Zhao, The Working Committee of the China National Newborn Growth Standards Project
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/25f8cd55ff5d41ed95f473c4b5a69057
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spelling	oai:doaj.org-article:25f8cd55ff5d41ed95f473c4b5a690572021-12-02T15:07:55ZConstruction of China national newborn growth standards based on a large low-risk sample10.1038/s41598-021-94606-62045-2322https://doaj.org/article/25f8cd55ff5d41ed95f473c4b5a690572021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-94606-6https://doaj.org/toc/2045-2322Abstract Most published newborn growth references are based on conventional monitoring data that usually included both low- and high-risk pregnancies. We sought to develop a set of neonatal growth standards constructed from only a large sample of low-risk pregnancies. A total of 24,375 naturally conceived singleton live births with gestational ages of 24–42 weeks were collected in 69 hospitals in thirteen Chinese cities between 2015 and 2018. Unhealthy infants or those with high-risk mother were excluded. Smoothed percentile curves of six anthropometric indicators were established using the Generalized Additive Model for Location, Scale and Shape. The 3rd, 10th, 25th, 50th, 75th, 90th, and 97th percentile references for birth weight, length, head circumference, weight/length, body mass index, and ponderal index were calculated for neonates with gestational ages of 24–42 weeks. This set of neonatal growth standards with six anthropometric indicators can provide more tools for growth and nutrition assessment and body proportionality in neonatal clinical practice. These standards might also help to show the differences between growth curves based on low-risk and mixed low- and high-risk pregnancies.Xin-Nan ZongHui LiYa-Qin ZhangHua-Hong WuGeng-Li ZhaoThe Working Committee of the China National Newborn Growth Standards ProjectNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Xin-Nan Zong Hui Li Ya-Qin Zhang Hua-Hong Wu Geng-Li Zhao The Working Committee of the China National Newborn Growth Standards Project Construction of China national newborn growth standards based on a large low-risk sample
description	Abstract Most published newborn growth references are based on conventional monitoring data that usually included both low- and high-risk pregnancies. We sought to develop a set of neonatal growth standards constructed from only a large sample of low-risk pregnancies. A total of 24,375 naturally conceived singleton live births with gestational ages of 24–42 weeks were collected in 69 hospitals in thirteen Chinese cities between 2015 and 2018. Unhealthy infants or those with high-risk mother were excluded. Smoothed percentile curves of six anthropometric indicators were established using the Generalized Additive Model for Location, Scale and Shape. The 3rd, 10th, 25th, 50th, 75th, 90th, and 97th percentile references for birth weight, length, head circumference, weight/length, body mass index, and ponderal index were calculated for neonates with gestational ages of 24–42 weeks. This set of neonatal growth standards with six anthropometric indicators can provide more tools for growth and nutrition assessment and body proportionality in neonatal clinical practice. These standards might also help to show the differences between growth curves based on low-risk and mixed low- and high-risk pregnancies.
format	article
author	Xin-Nan Zong Hui Li Ya-Qin Zhang Hua-Hong Wu Geng-Li Zhao The Working Committee of the China National Newborn Growth Standards Project
author_facet	Xin-Nan Zong Hui Li Ya-Qin Zhang Hua-Hong Wu Geng-Li Zhao The Working Committee of the China National Newborn Growth Standards Project
author_sort	Xin-Nan Zong
title	Construction of China national newborn growth standards based on a large low-risk sample
title_short	Construction of China national newborn growth standards based on a large low-risk sample
title_full	Construction of China national newborn growth standards based on a large low-risk sample
title_fullStr	Construction of China national newborn growth standards based on a large low-risk sample
title_full_unstemmed	Construction of China national newborn growth standards based on a large low-risk sample
title_sort	construction of china national newborn growth standards based on a large low-risk sample
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/25f8cd55ff5d41ed95f473c4b5a69057
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Construction of China national newborn growth standards based on a large low-risk sample

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