Francisella novicida Mutant XWK4 Triggers Robust Inflammasome Activation Favoring Infection

Bacterial infection tendentiously triggers inflammasome activation, whereas the roles of inflammasome activation in host defense against diverse infections remain unclear. Here, we identified that an ASC-dependent inflammasome activation played opposite roles in host defense against Francisella novi...

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Autores principales: Yu Guo, Rudi Mao, Qingqing Xie, Xiaojie Cheng, Tao Xu, Xiaoyuan Wang, Yan Du, Xiaopeng Qi
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/25f9f56fa42e4f47a6087e827c382998
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