A Fast Bubble Detection Method in Microtubes Based on Pulsed Ultrasound

In the process of biological microfluidic manipulation, the bubbles generated in the tube will seriously reduce the gauging accuracy. This paper introduces an improving method that can estimate the size of microbubbles in real time. Hence, the measurement data of the liquid volume can be modified ac...

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Autores principales: Yiqing Li, Junwu Wu, Leijie Fu, Jinju Wang
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:2605cf74a1cd499b81333dfe26654b832021-11-25T18:23:45ZA Fast Bubble Detection Method in Microtubes Based on Pulsed Ultrasound10.3390/mi121114022072-666Xhttps://doaj.org/article/2605cf74a1cd499b81333dfe26654b832021-11-01T00:00:00Zhttps://www.mdpi.com/2072-666X/12/11/1402https://doaj.org/toc/2072-666XIn the process of biological microfluidic manipulation, the bubbles generated in the tube will seriously reduce the gauging accuracy. This paper introduces an improving method that can estimate the size of microbubbles in real time. Hence, the measurement data of the liquid volume can be modified according to this method. A microbubble detector based on the pulsed-ultrasound method was studied, including the device structure and the working principle. The assessment formula of the microbubbles in the tube was derived from the simulation results, which adopted the two-phase theory. The digital image processing method was applied to fulfill the microbubble calibration. This detection method was applied to measure the microbubbles in the tube and to modify the flow volume in a timely manner. The results of the experiments showed that this method is effective at improving the microflow gauging accuracy.Yiqing LiJunwu WuLeijie FuJinju WangMDPI AGarticlepulsed-ultrasoundmicrobubbletwo-phase flowflow gauging accuracyMechanical engineering and machineryTJ1-1570ENMicromachines, Vol 12, Iss 1402, p 1402 (2021)
institution DOAJ
collection DOAJ
language EN
topic pulsed-ultrasound
microbubble
two-phase flow
flow gauging accuracy
Mechanical engineering and machinery
TJ1-1570
spellingShingle pulsed-ultrasound
microbubble
two-phase flow
flow gauging accuracy
Mechanical engineering and machinery
TJ1-1570
Yiqing Li
Junwu Wu
Leijie Fu
Jinju Wang
A Fast Bubble Detection Method in Microtubes Based on Pulsed Ultrasound
description In the process of biological microfluidic manipulation, the bubbles generated in the tube will seriously reduce the gauging accuracy. This paper introduces an improving method that can estimate the size of microbubbles in real time. Hence, the measurement data of the liquid volume can be modified according to this method. A microbubble detector based on the pulsed-ultrasound method was studied, including the device structure and the working principle. The assessment formula of the microbubbles in the tube was derived from the simulation results, which adopted the two-phase theory. The digital image processing method was applied to fulfill the microbubble calibration. This detection method was applied to measure the microbubbles in the tube and to modify the flow volume in a timely manner. The results of the experiments showed that this method is effective at improving the microflow gauging accuracy.
format article
author Yiqing Li
Junwu Wu
Leijie Fu
Jinju Wang
author_facet Yiqing Li
Junwu Wu
Leijie Fu
Jinju Wang
author_sort Yiqing Li
title A Fast Bubble Detection Method in Microtubes Based on Pulsed Ultrasound
title_short A Fast Bubble Detection Method in Microtubes Based on Pulsed Ultrasound
title_full A Fast Bubble Detection Method in Microtubes Based on Pulsed Ultrasound
title_fullStr A Fast Bubble Detection Method in Microtubes Based on Pulsed Ultrasound
title_full_unstemmed A Fast Bubble Detection Method in Microtubes Based on Pulsed Ultrasound
title_sort fast bubble detection method in microtubes based on pulsed ultrasound
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/2605cf74a1cd499b81333dfe26654b83
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AT jinjuwang afastbubbledetectionmethodinmicrotubesbasedonpulsedultrasound
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