Transcription-factor-mediated DNA looping probed by high-resolution, single-molecule imaging in live E. coli cells.
DNA looping mediated by transcription factors plays critical roles in prokaryotic gene regulation. The "genetic switch" of bacteriophage λ determines whether a prophage stays incorporated in the E. coli chromosome or enters the lytic cycle of phage propagation and cell lysis. Past studies...
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| Auteurs principaux: | , , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2013
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| Accès en ligne: | https://doaj.org/article/260c41e554f34ee1a1db701629ce7e6c |
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