Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA

Bacterial small RNA SgrS binds and regulates its primary target, ptsG mRNA. Here the authors employ Sort-Seq and super resolution imaging to investigate in vivo target recognition and rejection kinetics of SgrS.

Guardado en:
Detalles Bibliográficos
Autores principales: Anustup Poddar, Muhammad S. Azam, Tunc Kayikcioglu, Maksym Bobrovskyy, Jichuan Zhang, Xiangqian Ma, Piyush Labhsetwar, Jingyi Fei, Digvijay Singh, Zaida Luthey-Schulten, Carin K. Vanderpool, Taekjip Ha
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/260d7031d6064787a1c0ef3b7e025390
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:260d7031d6064787a1c0ef3b7e025390
record_format dspace
spelling oai:doaj.org-article:260d7031d6064787a1c0ef3b7e0253902021-12-02T13:30:15ZEffects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA10.1038/s41467-021-21144-02041-1723https://doaj.org/article/260d7031d6064787a1c0ef3b7e0253902021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21144-0https://doaj.org/toc/2041-1723Bacterial small RNA SgrS binds and regulates its primary target, ptsG mRNA. Here the authors employ Sort-Seq and super resolution imaging to investigate in vivo target recognition and rejection kinetics of SgrS.Anustup PoddarMuhammad S. AzamTunc KayikciogluMaksym BobrovskyyJichuan ZhangXiangqian MaPiyush LabhsetwarJingyi FeiDigvijay SinghZaida Luthey-SchultenCarin K. VanderpoolTaekjip HaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anustup Poddar
Muhammad S. Azam
Tunc Kayikcioglu
Maksym Bobrovskyy
Jichuan Zhang
Xiangqian Ma
Piyush Labhsetwar
Jingyi Fei
Digvijay Singh
Zaida Luthey-Schulten
Carin K. Vanderpool
Taekjip Ha
Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA
description Bacterial small RNA SgrS binds and regulates its primary target, ptsG mRNA. Here the authors employ Sort-Seq and super resolution imaging to investigate in vivo target recognition and rejection kinetics of SgrS.
format article
author Anustup Poddar
Muhammad S. Azam
Tunc Kayikcioglu
Maksym Bobrovskyy
Jichuan Zhang
Xiangqian Ma
Piyush Labhsetwar
Jingyi Fei
Digvijay Singh
Zaida Luthey-Schulten
Carin K. Vanderpool
Taekjip Ha
author_facet Anustup Poddar
Muhammad S. Azam
Tunc Kayikcioglu
Maksym Bobrovskyy
Jichuan Zhang
Xiangqian Ma
Piyush Labhsetwar
Jingyi Fei
Digvijay Singh
Zaida Luthey-Schulten
Carin K. Vanderpool
Taekjip Ha
author_sort Anustup Poddar
title Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA
title_short Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA
title_full Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA
title_fullStr Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA
title_full_unstemmed Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA
title_sort effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small rna
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/260d7031d6064787a1c0ef3b7e025390
work_keys_str_mv AT anustuppoddar effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT muhammadsazam effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT tunckayikcioglu effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT maksymbobrovskyy effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT jichuanzhang effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT xiangqianma effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT piyushlabhsetwar effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT jingyifei effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT digvijaysingh effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT zaidalutheyschulten effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT carinkvanderpool effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
AT taekjipha effectsofindividualbasepairsoninvivotargetsearchanddestructionkineticsofbacterialsmallrna
_version_ 1718392903833747456