β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis
Mutations affecting sialylation and galactosylation affect megakaryocyte function and thrombopoiesis. Here the authors show that the enzyme β4GalT1 regulates thrombopoiesis and hematopoietic stem cell homeostasis by controlling beta-1 integrin function.
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
|
| Subjects: | |
| Online Access: | https://doaj.org/article/260eeeaaa02b43dda46cc8c8f666fa3c |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|