A kinetically controlled platform for ligand-oligonucleotide transduction

Ligand-oligonucleotide interactions can integrate both small molecules and proteins into nucleic acid-based circuits. Here the authors design ligand-aptamer complexes to control strand-displacement reactions for versatile ligand transduction.

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Detalles Bibliográficos
Autores principales: Qiu-Long Zhang, Liang-Liang Wang, Yan Liu, Jiao Lin, Liang Xu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2617e0c70a9546e486efafce3118f9ff
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Descripción
Sumario:Ligand-oligonucleotide interactions can integrate both small molecules and proteins into nucleic acid-based circuits. Here the authors design ligand-aptamer complexes to control strand-displacement reactions for versatile ligand transduction.