A kinetically controlled platform for ligand-oligonucleotide transduction
Ligand-oligonucleotide interactions can integrate both small molecules and proteins into nucleic acid-based circuits. Here the authors design ligand-aptamer complexes to control strand-displacement reactions for versatile ligand transduction.
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Nature Portfolio
2021
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oai:doaj.org-article:2617e0c70a9546e486efafce3118f9ff2021-12-02T14:53:37ZA kinetically controlled platform for ligand-oligonucleotide transduction10.1038/s41467-021-24962-42041-1723https://doaj.org/article/2617e0c70a9546e486efafce3118f9ff2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24962-4https://doaj.org/toc/2041-1723Ligand-oligonucleotide interactions can integrate both small molecules and proteins into nucleic acid-based circuits. Here the authors design ligand-aptamer complexes to control strand-displacement reactions for versatile ligand transduction.Qiu-Long ZhangLiang-Liang WangYan LiuJiao LinLiang XuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021) |
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Science Q |
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Science Q Qiu-Long Zhang Liang-Liang Wang Yan Liu Jiao Lin Liang Xu A kinetically controlled platform for ligand-oligonucleotide transduction |
description |
Ligand-oligonucleotide interactions can integrate both small molecules and proteins into nucleic acid-based circuits. Here the authors design ligand-aptamer complexes to control strand-displacement reactions for versatile ligand transduction. |
format |
article |
author |
Qiu-Long Zhang Liang-Liang Wang Yan Liu Jiao Lin Liang Xu |
author_facet |
Qiu-Long Zhang Liang-Liang Wang Yan Liu Jiao Lin Liang Xu |
author_sort |
Qiu-Long Zhang |
title |
A kinetically controlled platform for ligand-oligonucleotide transduction |
title_short |
A kinetically controlled platform for ligand-oligonucleotide transduction |
title_full |
A kinetically controlled platform for ligand-oligonucleotide transduction |
title_fullStr |
A kinetically controlled platform for ligand-oligonucleotide transduction |
title_full_unstemmed |
A kinetically controlled platform for ligand-oligonucleotide transduction |
title_sort |
kinetically controlled platform for ligand-oligonucleotide transduction |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/2617e0c70a9546e486efafce3118f9ff |
work_keys_str_mv |
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_version_ |
1718389372036841472 |