A kinetically controlled platform for ligand-oligonucleotide transduction

Ligand-oligonucleotide interactions can integrate both small molecules and proteins into nucleic acid-based circuits. Here the authors design ligand-aptamer complexes to control strand-displacement reactions for versatile ligand transduction.

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Autores principales: Qiu-Long Zhang, Liang-Liang Wang, Yan Liu, Jiao Lin, Liang Xu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2617e0c70a9546e486efafce3118f9ff
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spelling oai:doaj.org-article:2617e0c70a9546e486efafce3118f9ff2021-12-02T14:53:37ZA kinetically controlled platform for ligand-oligonucleotide transduction10.1038/s41467-021-24962-42041-1723https://doaj.org/article/2617e0c70a9546e486efafce3118f9ff2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24962-4https://doaj.org/toc/2041-1723Ligand-oligonucleotide interactions can integrate both small molecules and proteins into nucleic acid-based circuits. Here the authors design ligand-aptamer complexes to control strand-displacement reactions for versatile ligand transduction.Qiu-Long ZhangLiang-Liang WangYan LiuJiao LinLiang XuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qiu-Long Zhang
Liang-Liang Wang
Yan Liu
Jiao Lin
Liang Xu
A kinetically controlled platform for ligand-oligonucleotide transduction
description Ligand-oligonucleotide interactions can integrate both small molecules and proteins into nucleic acid-based circuits. Here the authors design ligand-aptamer complexes to control strand-displacement reactions for versatile ligand transduction.
format article
author Qiu-Long Zhang
Liang-Liang Wang
Yan Liu
Jiao Lin
Liang Xu
author_facet Qiu-Long Zhang
Liang-Liang Wang
Yan Liu
Jiao Lin
Liang Xu
author_sort Qiu-Long Zhang
title A kinetically controlled platform for ligand-oligonucleotide transduction
title_short A kinetically controlled platform for ligand-oligonucleotide transduction
title_full A kinetically controlled platform for ligand-oligonucleotide transduction
title_fullStr A kinetically controlled platform for ligand-oligonucleotide transduction
title_full_unstemmed A kinetically controlled platform for ligand-oligonucleotide transduction
title_sort kinetically controlled platform for ligand-oligonucleotide transduction
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/2617e0c70a9546e486efafce3118f9ff
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