An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Abstract There is accumulating evidence of endothelial dysfunction, muscle and cerebral hypoperfusion in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In this paper we deduce the pathomechanisms resulting in central nervous pathology and the myriad of neurocognitive symptoms. We outli...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Klaus J. Wirth, Carmen Scheibenbogen, Friedemann Paul
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Chronic Fatigue Syndrome Myalgic Encephalomyelitis Post-Covid-19 syndrome Neurological symptoms Cognitive impairment Brain fog Medicine R
Acceso en línea:	https://doaj.org/article/261a851943b14f72a645fdaea0426c0e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:261a851943b14f72a645fdaea0426c0e
record_format	dspace
spelling	oai:doaj.org-article:261a851943b14f72a645fdaea0426c0e2021-11-28T12:06:49ZAn attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome10.1186/s12967-021-03143-31479-5876https://doaj.org/article/261a851943b14f72a645fdaea0426c0e2021-11-01T00:00:00Zhttps://doi.org/10.1186/s12967-021-03143-3https://doaj.org/toc/1479-5876Abstract There is accumulating evidence of endothelial dysfunction, muscle and cerebral hypoperfusion in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In this paper we deduce the pathomechanisms resulting in central nervous pathology and the myriad of neurocognitive symptoms. We outline tentative mechanisms of impaired cerebral blood flow, increase in intracranial pressure and central adrenergic hyperactivity and how they can well explain the key symptoms of cognitive impairment, brain fog, headache, hypersensitivity, sleep disturbances and dysautonomia.Klaus J. WirthCarmen ScheibenbogenFriedemann PaulBMCarticleChronic Fatigue SyndromeMyalgic EncephalomyelitisPost-Covid-19 syndromeNeurological symptomsCognitive impairmentBrain fogMedicineRENJournal of Translational Medicine, Vol 19, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Chronic Fatigue Syndrome Myalgic Encephalomyelitis Post-Covid-19 syndrome Neurological symptoms Cognitive impairment Brain fog Medicine R
spellingShingle	Chronic Fatigue Syndrome Myalgic Encephalomyelitis Post-Covid-19 syndrome Neurological symptoms Cognitive impairment Brain fog Medicine R Klaus J. Wirth Carmen Scheibenbogen Friedemann Paul An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
description	Abstract There is accumulating evidence of endothelial dysfunction, muscle and cerebral hypoperfusion in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In this paper we deduce the pathomechanisms resulting in central nervous pathology and the myriad of neurocognitive symptoms. We outline tentative mechanisms of impaired cerebral blood flow, increase in intracranial pressure and central adrenergic hyperactivity and how they can well explain the key symptoms of cognitive impairment, brain fog, headache, hypersensitivity, sleep disturbances and dysautonomia.
format	article
author	Klaus J. Wirth Carmen Scheibenbogen Friedemann Paul
author_facet	Klaus J. Wirth Carmen Scheibenbogen Friedemann Paul
author_sort	Klaus J. Wirth
title	An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
title_short	An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
title_full	An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
title_fullStr	An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
title_full_unstemmed	An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
title_sort	attempt to explain the neurological symptoms of myalgic encephalomyelitis/chronic fatigue syndrome
publisher	BMC
publishDate	2021
url	https://doaj.org/article/261a851943b14f72a645fdaea0426c0e
work_keys_str_mv	AT klausjwirth anattempttoexplaintheneurologicalsymptomsofmyalgicencephalomyelitischronicfatiguesyndrome AT carmenscheibenbogen anattempttoexplaintheneurologicalsymptomsofmyalgicencephalomyelitischronicfatiguesyndrome AT friedemannpaul anattempttoexplaintheneurologicalsymptomsofmyalgicencephalomyelitischronicfatiguesyndrome AT klausjwirth attempttoexplaintheneurologicalsymptomsofmyalgicencephalomyelitischronicfatiguesyndrome AT carmenscheibenbogen attempttoexplaintheneurologicalsymptomsofmyalgicencephalomyelitischronicfatiguesyndrome AT friedemannpaul attempttoexplaintheneurologicalsymptomsofmyalgicencephalomyelitischronicfatiguesyndrome
_version_	1718408188251865088

An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Ejemplares similares