Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC

KdpFABC is a high-affinity bacterial K+ pump which combines the ion channel-like KdpA and the P-type ATPase KdpB. Here, the authors elucidate the mechanisms underlying transport and the coupling to ATP hydrolysis, and provide evidence that ions are transported via an intersubunit tunnel through KdpA...

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Auteurs principaux: Jakob M. Silberberg, Robin A. Corey, Lisa Hielkema, Charlott Stock, Phillip J. Stansfeld, Cristina Paulino, Inga Hänelt
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/2620f43c74cb4b05a260da650d8ad4ff
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spelling oai:doaj.org-article:2620f43c74cb4b05a260da650d8ad4ff2021-12-02T19:02:28ZDeciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC10.1038/s41467-021-25242-x2041-1723https://doaj.org/article/2620f43c74cb4b05a260da650d8ad4ff2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25242-xhttps://doaj.org/toc/2041-1723KdpFABC is a high-affinity bacterial K+ pump which combines the ion channel-like KdpA and the P-type ATPase KdpB. Here, the authors elucidate the mechanisms underlying transport and the coupling to ATP hydrolysis, and provide evidence that ions are transported via an intersubunit tunnel through KdpA and KdpB.Jakob M. SilberbergRobin A. CoreyLisa HielkemaCharlott StockPhillip J. StansfeldCristina PaulinoInga HäneltNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jakob M. Silberberg
Robin A. Corey
Lisa Hielkema
Charlott Stock
Phillip J. Stansfeld
Cristina Paulino
Inga Hänelt
Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
description KdpFABC is a high-affinity bacterial K+ pump which combines the ion channel-like KdpA and the P-type ATPase KdpB. Here, the authors elucidate the mechanisms underlying transport and the coupling to ATP hydrolysis, and provide evidence that ions are transported via an intersubunit tunnel through KdpA and KdpB.
format article
author Jakob M. Silberberg
Robin A. Corey
Lisa Hielkema
Charlott Stock
Phillip J. Stansfeld
Cristina Paulino
Inga Hänelt
author_facet Jakob M. Silberberg
Robin A. Corey
Lisa Hielkema
Charlott Stock
Phillip J. Stansfeld
Cristina Paulino
Inga Hänelt
author_sort Jakob M. Silberberg
title Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
title_short Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
title_full Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
title_fullStr Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
title_full_unstemmed Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
title_sort deciphering ion transport and atpase coupling in the intersubunit tunnel of kdpfabc
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/2620f43c74cb4b05a260da650d8ad4ff
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AT lisahielkema decipheringiontransportandatpasecouplingintheintersubunittunnelofkdpfabc
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