Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC

KdpFABC is a high-affinity bacterial K+ pump which combines the ion channel-like KdpA and the P-type ATPase KdpB. Here, the authors elucidate the mechanisms underlying transport and the coupling to ATP hydrolysis, and provide evidence that ions are transported via an intersubunit tunnel through KdpA...

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Main Authors:	Jakob M. Silberberg, Robin A. Corey, Lisa Hielkema, Charlott Stock, Phillip J. Stansfeld, Cristina Paulino, Inga Hänelt
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Science Q
Online Access:	https://doaj.org/article/2620f43c74cb4b05a260da650d8ad4ff
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id	oai:doaj.org-article:2620f43c74cb4b05a260da650d8ad4ff
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spelling	oai:doaj.org-article:2620f43c74cb4b05a260da650d8ad4ff2021-12-02T19:02:28ZDeciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC10.1038/s41467-021-25242-x2041-1723https://doaj.org/article/2620f43c74cb4b05a260da650d8ad4ff2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25242-xhttps://doaj.org/toc/2041-1723KdpFABC is a high-affinity bacterial K+ pump which combines the ion channel-like KdpA and the P-type ATPase KdpB. Here, the authors elucidate the mechanisms underlying transport and the coupling to ATP hydrolysis, and provide evidence that ions are transported via an intersubunit tunnel through KdpA and KdpB.Jakob M. SilberbergRobin A. CoreyLisa HielkemaCharlott StockPhillip J. StansfeldCristina PaulinoInga HäneltNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jakob M. Silberberg Robin A. Corey Lisa Hielkema Charlott Stock Phillip J. Stansfeld Cristina Paulino Inga Hänelt Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
description	KdpFABC is a high-affinity bacterial K+ pump which combines the ion channel-like KdpA and the P-type ATPase KdpB. Here, the authors elucidate the mechanisms underlying transport and the coupling to ATP hydrolysis, and provide evidence that ions are transported via an intersubunit tunnel through KdpA and KdpB.
format	article
author	Jakob M. Silberberg Robin A. Corey Lisa Hielkema Charlott Stock Phillip J. Stansfeld Cristina Paulino Inga Hänelt
author_facet	Jakob M. Silberberg Robin A. Corey Lisa Hielkema Charlott Stock Phillip J. Stansfeld Cristina Paulino Inga Hänelt
author_sort	Jakob M. Silberberg
title	Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
title_short	Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
title_full	Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
title_fullStr	Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
title_full_unstemmed	Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
title_sort	deciphering ion transport and atpase coupling in the intersubunit tunnel of kdpfabc
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2620f43c74cb4b05a260da650d8ad4ff
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Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC

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