Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping

Nanopore sensors have shown tremendous potential for biomolecule sensing, though the diffusion-controlled capture can limit the speed of analysis. Here, the authors report a dielectrophoretic method to concentrate DNA near the tip of a nanopore, reducing the limit of detection by three orders of mag...

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Autores principales:	Kevin J. Freedman, Lauren M. Otto, Aleksandar P. Ivanov, Avijit Barik, Sang-Hyun Oh, Joshua B. Edel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/262317543d0c4b2896bf8cc7932ea005
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spelling	oai:doaj.org-article:262317543d0c4b2896bf8cc7932ea0052021-12-02T14:38:55ZNanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping10.1038/ncomms102172041-1723https://doaj.org/article/262317543d0c4b2896bf8cc7932ea0052016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10217https://doaj.org/toc/2041-1723Nanopore sensors have shown tremendous potential for biomolecule sensing, though the diffusion-controlled capture can limit the speed of analysis. Here, the authors report a dielectrophoretic method to concentrate DNA near the tip of a nanopore, reducing the limit of detection by three orders of magnitude.Kevin J. FreedmanLauren M. OttoAleksandar P. IvanovAvijit BarikSang-Hyun OhJoshua B. EdelNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kevin J. Freedman Lauren M. Otto Aleksandar P. Ivanov Avijit Barik Sang-Hyun Oh Joshua B. Edel Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping
description	Nanopore sensors have shown tremendous potential for biomolecule sensing, though the diffusion-controlled capture can limit the speed of analysis. Here, the authors report a dielectrophoretic method to concentrate DNA near the tip of a nanopore, reducing the limit of detection by three orders of magnitude.
format	article
author	Kevin J. Freedman Lauren M. Otto Aleksandar P. Ivanov Avijit Barik Sang-Hyun Oh Joshua B. Edel
author_facet	Kevin J. Freedman Lauren M. Otto Aleksandar P. Ivanov Avijit Barik Sang-Hyun Oh Joshua B. Edel
author_sort	Kevin J. Freedman
title	Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping
title_short	Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping
title_full	Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping
title_fullStr	Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping
title_full_unstemmed	Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping
title_sort	nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/262317543d0c4b2896bf8cc7932ea005
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Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping

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