New Multidrug Efflux Inhibitors for Gram-Negative Bacteria

ABSTRACT Active efflux of antibiotics preventing their accumulation to toxic intracellular concentrations contributes to clinically relevant multidrug resistance. Inhibition of active efflux potentiates antibiotic activity, indicating that efflux inhibitors could be used in combination with antibiot...

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Autores principales: Robert L. Marshall, Georgina S. Lloyd, Amelia J. Lawler, Sarah J. Element, Jaswant Kaur, Maria Laura Ciusa, Vito Ricci, Andreas Tschumi, Holger Kühne, Luke J. Alderwick, Laura J. V. Piddock
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/2629c888b070459bbab02735e914fc43
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