Indications and outcomes for intravitreal injection of C3F8 gas for symptomatic vitreomacular traction

Abstract To evaluate the indications and outcomes of perfluoropropane (C3F8) gas injection for symptomatic vitreomacular traction (VMT). A retrospective analysis of eyes with VMT treated with 0.3 mL of C3F8 gas was performed. Patients were not asked to posture after gas injection. In phakic patients...

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Autores principales: Josef Guber, Celine Rusch, Ivo Guber, Hendrik P. N. Scholl, Christophe Valmaggia
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/262a2c547a764ea281122eac733ce5a7
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spelling oai:doaj.org-article:262a2c547a764ea281122eac733ce5a72021-12-02T19:12:31ZIndications and outcomes for intravitreal injection of C3F8 gas for symptomatic vitreomacular traction10.1038/s41598-021-97639-z2045-2322https://doaj.org/article/262a2c547a764ea281122eac733ce5a72021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-97639-zhttps://doaj.org/toc/2045-2322Abstract To evaluate the indications and outcomes of perfluoropropane (C3F8) gas injection for symptomatic vitreomacular traction (VMT). A retrospective analysis of eyes with VMT treated with 0.3 mL of C3F8 gas was performed. Patients were not asked to posture after gas injection. In phakic patients, cataract surgery was performed simultaneously. Patients were examined after one week and one month postoperatively. Twenty-nine consecutive eyes of 26 patients with symptomatic VMT who underwent pneumatic vitreolysis were included. A complete posterior vitreous detachment was achieved in 18 eyes (62.1%) after a single gas injection at the final visit. The rate of posterior vitreous detachment was reduced significantly with the presence of epiretinal membrane (ERM) (p = 0.003). Three eyes formed a macular hole (MH) postoperatively and another eye developed a retinal detachment. Mean visual acuity increased significantly after one month (p < 0.008). Pneumatic vitreolysis is a viable option for treating VMT with few adverse events. Patient with concomitant ERM had a significantly lower success rate.Josef GuberCeline RuschIvo GuberHendrik P. N. SchollChristophe ValmaggiaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Josef Guber
Celine Rusch
Ivo Guber
Hendrik P. N. Scholl
Christophe Valmaggia
Indications and outcomes for intravitreal injection of C3F8 gas for symptomatic vitreomacular traction
description Abstract To evaluate the indications and outcomes of perfluoropropane (C3F8) gas injection for symptomatic vitreomacular traction (VMT). A retrospective analysis of eyes with VMT treated with 0.3 mL of C3F8 gas was performed. Patients were not asked to posture after gas injection. In phakic patients, cataract surgery was performed simultaneously. Patients were examined after one week and one month postoperatively. Twenty-nine consecutive eyes of 26 patients with symptomatic VMT who underwent pneumatic vitreolysis were included. A complete posterior vitreous detachment was achieved in 18 eyes (62.1%) after a single gas injection at the final visit. The rate of posterior vitreous detachment was reduced significantly with the presence of epiretinal membrane (ERM) (p = 0.003). Three eyes formed a macular hole (MH) postoperatively and another eye developed a retinal detachment. Mean visual acuity increased significantly after one month (p < 0.008). Pneumatic vitreolysis is a viable option for treating VMT with few adverse events. Patient with concomitant ERM had a significantly lower success rate.
format article
author Josef Guber
Celine Rusch
Ivo Guber
Hendrik P. N. Scholl
Christophe Valmaggia
author_facet Josef Guber
Celine Rusch
Ivo Guber
Hendrik P. N. Scholl
Christophe Valmaggia
author_sort Josef Guber
title Indications and outcomes for intravitreal injection of C3F8 gas for symptomatic vitreomacular traction
title_short Indications and outcomes for intravitreal injection of C3F8 gas for symptomatic vitreomacular traction
title_full Indications and outcomes for intravitreal injection of C3F8 gas for symptomatic vitreomacular traction
title_fullStr Indications and outcomes for intravitreal injection of C3F8 gas for symptomatic vitreomacular traction
title_full_unstemmed Indications and outcomes for intravitreal injection of C3F8 gas for symptomatic vitreomacular traction
title_sort indications and outcomes for intravitreal injection of c3f8 gas for symptomatic vitreomacular traction
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/262a2c547a764ea281122eac733ce5a7
work_keys_str_mv AT josefguber indicationsandoutcomesforintravitrealinjectionofc3f8gasforsymptomaticvitreomaculartraction
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AT ivoguber indicationsandoutcomesforintravitrealinjectionofc3f8gasforsymptomaticvitreomaculartraction
AT hendrikpnscholl indicationsandoutcomesforintravitrealinjectionofc3f8gasforsymptomaticvitreomaculartraction
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