IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY

The aim of present work was to study IL-1β, IL-6, and TNFα levels in the patients with coronary artery disease (CAD) accompanied by anxiety and depression. We have revealed a significant increase in IL-6 and TNFα in the patients with ischemic CAD associated with comorbid affective disturbances, as c...

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Autores principales: S. N. Kozlova, A. V. Golubev, U. S. Krylova, K. A. Syssoev, E. V. Shlyakhto, N. G. Neznanov, Areg A. Totolian
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/262de37a72e24b29aa91936fe54cc055
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spelling oai:doaj.org-article:262de37a72e24b29aa91936fe54cc0552021-11-18T08:03:37ZIMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY1563-06252313-741X10.15789/1563-0625-2010-3-235-240https://doaj.org/article/262de37a72e24b29aa91936fe54cc0552014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/99https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XThe aim of present work was to study IL-1β, IL-6, and TNFα levels in the patients with coronary artery disease (CAD) accompanied by anxiety and depression. We have revealed a significant increase in IL-6 and TNFα in the patients with ischemic CAD associated with comorbid affective disturbances, as compared to the persons with CAD free of mood disorders. Our results support a «cytokine» hypothesis of affective disturbances in CAD patients, i.e., in cases associated with anxiety and depression.S. N. KozlovaA. V. GolubevU. S. KrylovaK. A. SyssoevE. V. ShlyakhtoN. G. NeznanovAreg A. TotolianSPb RAACIarticlecoronary artery diseasedepressionanxietycytokinesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 3, Pp 235-240 (2014)
institution DOAJ
collection DOAJ
language RU
topic coronary artery disease
depression
anxiety
cytokines
Immunologic diseases. Allergy
RC581-607
spellingShingle coronary artery disease
depression
anxiety
cytokines
Immunologic diseases. Allergy
RC581-607
S. N. Kozlova
A. V. Golubev
U. S. Krylova
K. A. Syssoev
E. V. Shlyakhto
N. G. Neznanov
Areg A. Totolian
IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY
description The aim of present work was to study IL-1β, IL-6, and TNFα levels in the patients with coronary artery disease (CAD) accompanied by anxiety and depression. We have revealed a significant increase in IL-6 and TNFα in the patients with ischemic CAD associated with comorbid affective disturbances, as compared to the persons with CAD free of mood disorders. Our results support a «cytokine» hypothesis of affective disturbances in CAD patients, i.e., in cases associated with anxiety and depression.
format article
author S. N. Kozlova
A. V. Golubev
U. S. Krylova
K. A. Syssoev
E. V. Shlyakhto
N. G. Neznanov
Areg A. Totolian
author_facet S. N. Kozlova
A. V. Golubev
U. S. Krylova
K. A. Syssoev
E. V. Shlyakhto
N. G. Neznanov
Areg A. Totolian
author_sort S. N. Kozlova
title IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY
title_short IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY
title_full IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY
title_fullStr IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY
title_full_unstemmed IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY
title_sort impact of cytokines upon comorbid states of coronary artery disease and affective disorders associated with depression and anxiety
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/262de37a72e24b29aa91936fe54cc055
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