IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY
The aim of present work was to study IL-1β, IL-6, and TNFα levels in the patients with coronary artery disease (CAD) accompanied by anxiety and depression. We have revealed a significant increase in IL-6 and TNFα in the patients with ischemic CAD associated with comorbid affective disturbances, as c...
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2014
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oai:doaj.org-article:262de37a72e24b29aa91936fe54cc0552021-11-18T08:03:37ZIMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY1563-06252313-741X10.15789/1563-0625-2010-3-235-240https://doaj.org/article/262de37a72e24b29aa91936fe54cc0552014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/99https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XThe aim of present work was to study IL-1β, IL-6, and TNFα levels in the patients with coronary artery disease (CAD) accompanied by anxiety and depression. We have revealed a significant increase in IL-6 and TNFα in the patients with ischemic CAD associated with comorbid affective disturbances, as compared to the persons with CAD free of mood disorders. Our results support a «cytokine» hypothesis of affective disturbances in CAD patients, i.e., in cases associated with anxiety and depression.S. N. KozlovaA. V. GolubevU. S. KrylovaK. A. SyssoevE. V. ShlyakhtoN. G. NeznanovAreg A. TotolianSPb RAACIarticlecoronary artery diseasedepressionanxietycytokinesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 3, Pp 235-240 (2014) |
institution |
DOAJ |
collection |
DOAJ |
language |
RU |
topic |
coronary artery disease depression anxiety cytokines Immunologic diseases. Allergy RC581-607 |
spellingShingle |
coronary artery disease depression anxiety cytokines Immunologic diseases. Allergy RC581-607 S. N. Kozlova A. V. Golubev U. S. Krylova K. A. Syssoev E. V. Shlyakhto N. G. Neznanov Areg A. Totolian IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY |
description |
The aim of present work was to study IL-1β, IL-6, and TNFα levels in the patients with coronary artery disease (CAD) accompanied by anxiety and depression. We have revealed a significant increase in IL-6 and TNFα in the patients with ischemic CAD associated with comorbid affective disturbances, as compared to the persons with CAD free of mood disorders. Our results support a «cytokine» hypothesis of affective disturbances in CAD patients, i.e., in cases associated with anxiety and depression. |
format |
article |
author |
S. N. Kozlova A. V. Golubev U. S. Krylova K. A. Syssoev E. V. Shlyakhto N. G. Neznanov Areg A. Totolian |
author_facet |
S. N. Kozlova A. V. Golubev U. S. Krylova K. A. Syssoev E. V. Shlyakhto N. G. Neznanov Areg A. Totolian |
author_sort |
S. N. Kozlova |
title |
IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY |
title_short |
IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY |
title_full |
IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY |
title_fullStr |
IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY |
title_full_unstemmed |
IMPACT OF CYTOKINES UPON COMORBID STATES OF CORONARY ARTERY DISEASE AND AFFECTIVE DISORDERS ASSOCIATED WITH DEPRESSION AND ANXIETY |
title_sort |
impact of cytokines upon comorbid states of coronary artery disease and affective disorders associated with depression and anxiety |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/262de37a72e24b29aa91936fe54cc055 |
work_keys_str_mv |
AT snkozlova impactofcytokinesuponcomorbidstatesofcoronaryarterydiseaseandaffectivedisordersassociatedwithdepressionandanxiety AT avgolubev impactofcytokinesuponcomorbidstatesofcoronaryarterydiseaseandaffectivedisordersassociatedwithdepressionandanxiety AT uskrylova impactofcytokinesuponcomorbidstatesofcoronaryarterydiseaseandaffectivedisordersassociatedwithdepressionandanxiety AT kasyssoev impactofcytokinesuponcomorbidstatesofcoronaryarterydiseaseandaffectivedisordersassociatedwithdepressionandanxiety AT evshlyakhto impactofcytokinesuponcomorbidstatesofcoronaryarterydiseaseandaffectivedisordersassociatedwithdepressionandanxiety AT ngneznanov impactofcytokinesuponcomorbidstatesofcoronaryarterydiseaseandaffectivedisordersassociatedwithdepressionandanxiety AT aregatotolian impactofcytokinesuponcomorbidstatesofcoronaryarterydiseaseandaffectivedisordersassociatedwithdepressionandanxiety |
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1718422531414687744 |