Copper-catalyzed carbo-difluoromethylation of alkenes via radical relay
Compounds that contain alkyl-difluoromethyl moieties are of interest for medicinal chemistry, but their synthesis is challenging. Here, the authors report a copper-catalyzed radical relay approach for the carbodifluoromethylation of alkenes that simultaneously introduces CF2H groups and complex alky...
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Autores principales: | Aijie Cai, Wenhao Yan, Xiaojun Zeng, Samson B. Zacate, Tzu-Hsuan Chao, Jeanette A. Krause, Mu-Jeng Cheng, Wei Liu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/2631e74ef56744c9b19881e8824bf0a4 |
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