Structural and Nonstructural Genes Contribute to the Genetic Diversity of RNA Viruses

ABSTRACT One paradigm to explain the complexity of viral RNA populations is that the low fidelity of the RNA-dependent RNA polymerase (RdRp) drives high mutation rates and consequently genetic diversity. Like most RNA viruses, wild-type yellow fever virus (YFV) replication is error-prone due to the...

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Auteurs principaux: Natalie D. Collins, Andrew S. Beck, Steven G. Widen, Thomas G. Wood, Stephen Higgs, Alan D. T. Barrett
Format: article
Langue:EN
Publié: American Society for Microbiology 2018
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Accès en ligne:https://doaj.org/article/263c1e1491294c0fb09dd7f95b9a0be7
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