Laminin regulates PDGFRβ+ cell stemness and muscle development

Muscle PDGFRβ+ cells are interstitial stem/progenitor cells with myogenic potential. Here, Yao et al. show that PDGFRβ+cell-derived laminin actively regulates their proliferation, differentiation and fate determination.

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Detalles Bibliográficos
Autores principales: Yao Yao, Erin H. Norris, Christopher E. Mason, Sidney Strickland
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/2644e49aaf0a4c4e98769edc416a6d6d
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Descripción
Sumario:Muscle PDGFRβ+ cells are interstitial stem/progenitor cells with myogenic potential. Here, Yao et al. show that PDGFRβ+cell-derived laminin actively regulates their proliferation, differentiation and fate determination.