Laminin regulates PDGFRβ+ cell stemness and muscle development

Muscle PDGFRβ+ cells are interstitial stem/progenitor cells with myogenic potential. Here, Yao et al. show that PDGFRβ+cell-derived laminin actively regulates their proliferation, differentiation and fate determination.

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Autores principales: Yao Yao, Erin H. Norris, Christopher E. Mason, Sidney Strickland
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/2644e49aaf0a4c4e98769edc416a6d6d
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spelling oai:doaj.org-article:2644e49aaf0a4c4e98769edc416a6d6d2021-12-02T15:34:54ZLaminin regulates PDGFRβ+ cell stemness and muscle development10.1038/ncomms114152041-1723https://doaj.org/article/2644e49aaf0a4c4e98769edc416a6d6d2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11415https://doaj.org/toc/2041-1723Muscle PDGFRβ+ cells are interstitial stem/progenitor cells with myogenic potential. Here, Yao et al. show that PDGFRβ+cell-derived laminin actively regulates their proliferation, differentiation and fate determination.Yao YaoErin H. NorrisChristopher E. MasonSidney StricklandNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yao Yao
Erin H. Norris
Christopher E. Mason
Sidney Strickland
Laminin regulates PDGFRβ+ cell stemness and muscle development
description Muscle PDGFRβ+ cells are interstitial stem/progenitor cells with myogenic potential. Here, Yao et al. show that PDGFRβ+cell-derived laminin actively regulates their proliferation, differentiation and fate determination.
format article
author Yao Yao
Erin H. Norris
Christopher E. Mason
Sidney Strickland
author_facet Yao Yao
Erin H. Norris
Christopher E. Mason
Sidney Strickland
author_sort Yao Yao
title Laminin regulates PDGFRβ+ cell stemness and muscle development
title_short Laminin regulates PDGFRβ+ cell stemness and muscle development
title_full Laminin regulates PDGFRβ+ cell stemness and muscle development
title_fullStr Laminin regulates PDGFRβ+ cell stemness and muscle development
title_full_unstemmed Laminin regulates PDGFRβ+ cell stemness and muscle development
title_sort laminin regulates pdgfrβ+ cell stemness and muscle development
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/2644e49aaf0a4c4e98769edc416a6d6d
work_keys_str_mv AT yaoyao lamininregulatespdgfrbcellstemnessandmuscledevelopment
AT erinhnorris lamininregulatespdgfrbcellstemnessandmuscledevelopment
AT christopheremason lamininregulatespdgfrbcellstemnessandmuscledevelopment
AT sidneystrickland lamininregulatespdgfrbcellstemnessandmuscledevelopment
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