Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging
The rod-shaped virus APBV1 is among the most thermostable viruses known. Here, Ptchelkine et al. determine its structure at near-atomic resolution, show that the DNA is packed as left-handed superhelix and identify extended hydrophobic interfaces that likely contribute to the extreme thermostability...
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Nature Portfolio
2017
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oai:doaj.org-article:2658d6e813804f9a970e1412f0a781652021-12-02T14:42:08ZUnique architecture of thermophilic archaeal virus APBV1 and its genome packaging10.1038/s41467-017-01668-02041-1723https://doaj.org/article/2658d6e813804f9a970e1412f0a781652017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01668-0https://doaj.org/toc/2041-1723The rod-shaped virus APBV1 is among the most thermostable viruses known. Here, Ptchelkine et al. determine its structure at near-atomic resolution, show that the DNA is packed as left-handed superhelix and identify extended hydrophobic interfaces that likely contribute to the extreme thermostability of the capsid.Denis PtchelkineAshley GillumTomohiro MochizukiSoizick Lucas-StaatYing LiuMart KrupovicSimon E. V. PhillipsDavid PrangishviliJuha T. HuiskonenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-6 (2017) |
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Science Q Denis Ptchelkine Ashley Gillum Tomohiro Mochizuki Soizick Lucas-Staat Ying Liu Mart Krupovic Simon E. V. Phillips David Prangishvili Juha T. Huiskonen Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging |
description |
The rod-shaped virus APBV1 is among the most thermostable viruses known. Here, Ptchelkine et al. determine its structure at near-atomic resolution, show that the DNA is packed as left-handed superhelix and identify extended hydrophobic interfaces that likely contribute to the extreme thermostability of the capsid. |
format |
article |
author |
Denis Ptchelkine Ashley Gillum Tomohiro Mochizuki Soizick Lucas-Staat Ying Liu Mart Krupovic Simon E. V. Phillips David Prangishvili Juha T. Huiskonen |
author_facet |
Denis Ptchelkine Ashley Gillum Tomohiro Mochizuki Soizick Lucas-Staat Ying Liu Mart Krupovic Simon E. V. Phillips David Prangishvili Juha T. Huiskonen |
author_sort |
Denis Ptchelkine |
title |
Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging |
title_short |
Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging |
title_full |
Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging |
title_fullStr |
Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging |
title_full_unstemmed |
Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging |
title_sort |
unique architecture of thermophilic archaeal virus apbv1 and its genome packaging |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/2658d6e813804f9a970e1412f0a78165 |
work_keys_str_mv |
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_version_ |
1718389740041928704 |