Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging

The rod-shaped virus APBV1 is among the most thermostable viruses known. Here, Ptchelkine et al. determine its structure at near-atomic resolution, show that the DNA is packed as left-handed superhelix and identify extended hydrophobic interfaces that likely contribute to the extreme thermostability...

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Autores principales: Denis Ptchelkine, Ashley Gillum, Tomohiro Mochizuki, Soizick Lucas-Staat, Ying Liu, Mart Krupovic, Simon E. V. Phillips, David Prangishvili, Juha T. Huiskonen
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2658d6e813804f9a970e1412f0a78165
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spelling oai:doaj.org-article:2658d6e813804f9a970e1412f0a781652021-12-02T14:42:08ZUnique architecture of thermophilic archaeal virus APBV1 and its genome packaging10.1038/s41467-017-01668-02041-1723https://doaj.org/article/2658d6e813804f9a970e1412f0a781652017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01668-0https://doaj.org/toc/2041-1723The rod-shaped virus APBV1 is among the most thermostable viruses known. Here, Ptchelkine et al. determine its structure at near-atomic resolution, show that the DNA is packed as left-handed superhelix and identify extended hydrophobic interfaces that likely contribute to the extreme thermostability of the capsid.Denis PtchelkineAshley GillumTomohiro MochizukiSoizick Lucas-StaatYing LiuMart KrupovicSimon E. V. PhillipsDavid PrangishviliJuha T. HuiskonenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-6 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Denis Ptchelkine
Ashley Gillum
Tomohiro Mochizuki
Soizick Lucas-Staat
Ying Liu
Mart Krupovic
Simon E. V. Phillips
David Prangishvili
Juha T. Huiskonen
Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging
description The rod-shaped virus APBV1 is among the most thermostable viruses known. Here, Ptchelkine et al. determine its structure at near-atomic resolution, show that the DNA is packed as left-handed superhelix and identify extended hydrophobic interfaces that likely contribute to the extreme thermostability of the capsid.
format article
author Denis Ptchelkine
Ashley Gillum
Tomohiro Mochizuki
Soizick Lucas-Staat
Ying Liu
Mart Krupovic
Simon E. V. Phillips
David Prangishvili
Juha T. Huiskonen
author_facet Denis Ptchelkine
Ashley Gillum
Tomohiro Mochizuki
Soizick Lucas-Staat
Ying Liu
Mart Krupovic
Simon E. V. Phillips
David Prangishvili
Juha T. Huiskonen
author_sort Denis Ptchelkine
title Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging
title_short Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging
title_full Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging
title_fullStr Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging
title_full_unstemmed Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging
title_sort unique architecture of thermophilic archaeal virus apbv1 and its genome packaging
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/2658d6e813804f9a970e1412f0a78165
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