Treatment of Secondary Mitral Regurgitation in Heart Failure: A Shifting Paradigm in the Wake of the COAPT Trial
Secondary mitral regurgitation (MR) is common in patients with left heart dysfunction and it is associated with poor outcomes. Findings from the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT) trial, pub...
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Radcliffe Medical Media
2020
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oai:doaj.org-article:2658dea05e4b40c199171b88e74c62c12021-12-04T16:03:18ZTreatment of Secondary Mitral Regurgitation in Heart Failure: A Shifting Paradigm in the Wake of the COAPT Trial10.15420/usc.2020.051758-390X1758-3896https://doaj.org/article/2658dea05e4b40c199171b88e74c62c12020-07-01T00:00:00Zhttps://www.uscjournal.com/articleindex/usc.2020.05https://doaj.org/toc/1758-3896https://doaj.org/toc/1758-390XSecondary mitral regurgitation (MR) is common in patients with left heart dysfunction and it is associated with poor outcomes. Findings from the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT) trial, published in 2018, suggest that in a subset of people with heart failure with secondary MR that persists despite optimization of guideline-directed medical therapies, there is now a role for percutaneous mitral valve repair using the MitraClip device. Defining which patients are most likely to benefit from MitraClip, and when, requires both a multidisciplinary approach centered on heart failure, as well as a recognition of the need for further research in this area.Kelly H SchlendorfJared O’LearyJoAnn LindenfeldRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENUS Cardiology Review , Vol 14, Iss , Pp - (2020) |
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DOAJ |
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DOAJ |
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EN |
| topic |
Diseases of the circulatory (Cardiovascular) system RC666-701 |
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Diseases of the circulatory (Cardiovascular) system RC666-701 Kelly H Schlendorf Jared O’Leary JoAnn Lindenfeld Treatment of Secondary Mitral Regurgitation in Heart Failure: A Shifting Paradigm in the Wake of the COAPT Trial |
| description |
Secondary mitral regurgitation (MR) is common in patients with left heart dysfunction and it is associated with poor outcomes. Findings from the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT) trial, published in 2018, suggest that in a subset of people with heart failure with secondary MR that persists despite optimization of guideline-directed medical therapies, there is now a role for percutaneous mitral valve repair using the MitraClip device. Defining which patients are most likely to benefit from MitraClip, and when, requires both a multidisciplinary approach centered on heart failure, as well as a recognition of the need for further research in this area. |
| format |
article |
| author |
Kelly H Schlendorf Jared O’Leary JoAnn Lindenfeld |
| author_facet |
Kelly H Schlendorf Jared O’Leary JoAnn Lindenfeld |
| author_sort |
Kelly H Schlendorf |
| title |
Treatment of Secondary Mitral Regurgitation in Heart Failure: A Shifting Paradigm in the Wake of the COAPT Trial |
| title_short |
Treatment of Secondary Mitral Regurgitation in Heart Failure: A Shifting Paradigm in the Wake of the COAPT Trial |
| title_full |
Treatment of Secondary Mitral Regurgitation in Heart Failure: A Shifting Paradigm in the Wake of the COAPT Trial |
| title_fullStr |
Treatment of Secondary Mitral Regurgitation in Heart Failure: A Shifting Paradigm in the Wake of the COAPT Trial |
| title_full_unstemmed |
Treatment of Secondary Mitral Regurgitation in Heart Failure: A Shifting Paradigm in the Wake of the COAPT Trial |
| title_sort |
treatment of secondary mitral regurgitation in heart failure: a shifting paradigm in the wake of the coapt trial |
| publisher |
Radcliffe Medical Media |
| publishDate |
2020 |
| url |
https://doaj.org/article/2658dea05e4b40c199171b88e74c62c1 |
| work_keys_str_mv |
AT kellyhschlendorf treatmentofsecondarymitralregurgitationinheartfailureashiftingparadigminthewakeofthecoapttrial AT jaredoleary treatmentofsecondarymitralregurgitationinheartfailureashiftingparadigminthewakeofthecoapttrial AT joannlindenfeld treatmentofsecondarymitralregurgitationinheartfailureashiftingparadigminthewakeofthecoapttrial |
| _version_ |
1718372722387451904 |